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Treatment Patterns, Healthcare Utilization, and Related Costs for Prurigo Nodularis in Sweden

VON KOBYLETZKI, Laura LU ; Metsini, Alexandra ; Regnell, Simon E. ; Carlberg, Michael ; Svensson, Åke LU and Antelmi, Annarita LU (2025) In Acta Dermato-Venereologica 105.
Abstract

Prurigo nodularis (PN) is a chronic, itchy, inflammatory skin condition that negatively affects quality of life. A study was undertaken to investigate the healthcare utilization, including treatment patterns and direct costs for specialist care, for PN in Sweden. Linkage cohorts were created from national Swedish patient and prescription registers, and the cost-per-patient database of PN adults in specialist care in Sweden from 2015 to 2020. Around 875 patients were registered annually with a specialist diagnosis of PN in Sweden, with 3,548 specialist visits per year on average. In patients with severe PN with AD, the most common treatment sequence was topical treatment with corticosteroids followed by systemic prednisolone and... (More)

Prurigo nodularis (PN) is a chronic, itchy, inflammatory skin condition that negatively affects quality of life. A study was undertaken to investigate the healthcare utilization, including treatment patterns and direct costs for specialist care, for PN in Sweden. Linkage cohorts were created from national Swedish patient and prescription registers, and the cost-per-patient database of PN adults in specialist care in Sweden from 2015 to 2020. Around 875 patients were registered annually with a specialist diagnosis of PN in Sweden, with 3,548 specialist visits per year on average. In patients with severe PN with AD, the most common treatment sequence was topical treatment with corticosteroids followed by systemic prednisolone and methotrexate (32.6%). More than one-fifth of individuals with PN, and most with severe PN, had treatment for more than 1 year. For in-and outpatient care, the mean cost per visit was €458.6 and per patient per year around €1,862. The total annual cost of PN patients is estimated to be €1.6 million in Sweden. A high proportion of patients are treated for years with several, often systemic, treatment sequels. Targeted treatments for PN might improve patients’ quality of life and reduce the high related costs for the healthcare system.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
costs, epidemiology, healthcare resource utilization, prurigo nodularis, treatment patterns
in
Acta Dermato-Venereologica
volume
105
article number
adv43730
publisher
Medical Journals Limited
external identifiers
  • scopus:105013687763
  • pmid:40824157
ISSN
0001-5555
DOI
10.2340/actadv.v105.43730
language
English
LU publication?
yes
id
b033488c-ab47-41e0-a127-8a678a18d1c7
date added to LUP
2025-11-19 09:44:41
date last changed
2025-11-20 03:00:12
@article{b033488c-ab47-41e0-a127-8a678a18d1c7,
  abstract     = {{<p>Prurigo nodularis (PN) is a chronic, itchy, inflammatory skin condition that negatively affects quality of life. A study was undertaken to investigate the healthcare utilization, including treatment patterns and direct costs for specialist care, for PN in Sweden. Linkage cohorts were created from national Swedish patient and prescription registers, and the cost-per-patient database of PN adults in specialist care in Sweden from 2015 to 2020. Around 875 patients were registered annually with a specialist diagnosis of PN in Sweden, with 3,548 specialist visits per year on average. In patients with severe PN with AD, the most common treatment sequence was topical treatment with corticosteroids followed by systemic prednisolone and methotrexate (32.6%). More than one-fifth of individuals with PN, and most with severe PN, had treatment for more than 1 year. For in-and outpatient care, the mean cost per visit was €458.6 and per patient per year around €1,862. The total annual cost of PN patients is estimated to be €1.6 million in Sweden. A high proportion of patients are treated for years with several, often systemic, treatment sequels. Targeted treatments for PN might improve patients’ quality of life and reduce the high related costs for the healthcare system.</p>}},
  author       = {{VON KOBYLETZKI, Laura and Metsini, Alexandra and Regnell, Simon E. and Carlberg, Michael and Svensson, Åke and Antelmi, Annarita}},
  issn         = {{0001-5555}},
  keywords     = {{costs; epidemiology; healthcare resource utilization; prurigo nodularis; treatment patterns}},
  language     = {{eng}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Treatment Patterns, Healthcare Utilization, and Related Costs for Prurigo Nodularis in Sweden}},
  url          = {{http://dx.doi.org/10.2340/actadv.v105.43730}},
  doi          = {{10.2340/actadv.v105.43730}},
  volume       = {{105}},
  year         = {{2025}},
}