Open chromatin and diabetes risk.
(2010) In Nature Genetics 42(3). p.190-192- Abstract
- A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes-associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and shows allele-specific enhancer activity, suggesting a potential mechanism for this disease association.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1552313
- author
- Groop, Leif LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nature Genetics
- volume
- 42
- issue
- 3
- pages
- 190 - 192
- publisher
- Nature Publishing Group
- external identifiers
-
- wos:000274912400003
- pmid:20179731
- scopus:77649099195
- pmid:20179731
- ISSN
- 1546-1718
- DOI
- 10.1038/ng0310-190
- language
- English
- LU publication?
- yes
- id
- b0b03479-1d37-48d3-996a-8213a62f15d1 (old id 1552313)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20179731?dopt=Abstract
- date added to LUP
- 2016-04-04 09:45:21
- date last changed
- 2024-01-12 17:52:48
@article{b0b03479-1d37-48d3-996a-8213a62f15d1,
abstract = {{A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes-associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and shows allele-specific enhancer activity, suggesting a potential mechanism for this disease association.}},
author = {{Groop, Leif}},
issn = {{1546-1718}},
language = {{eng}},
number = {{3}},
pages = {{190--192}},
publisher = {{Nature Publishing Group}},
series = {{Nature Genetics}},
title = {{Open chromatin and diabetes risk.}},
url = {{http://dx.doi.org/10.1038/ng0310-190}},
doi = {{10.1038/ng0310-190}},
volume = {{42}},
year = {{2010}},
}