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Optometrists’ Assessment of Pseudoexfoliation and Its Impact on Glaucoma Referrals

Landgren, Karin and Peters, Dorothea LU (2025) In Clinical Ophthalmology 19. p.1111-1118
Abstract

Purpose: To determine the frequency and accuracy of pseudoexfoliation syndrome (PEX) assessment in referrals from primary care optometrists before the new Swedish glaucoma guidelines were established, and to evaluate an optometrist’s ability to assess PEX. Patients and Methods: We studied PEX assessments in 95 referrals (95 patients,189 eyes) with elevated intraocular pressure (IOP) from optometrists to the Skåne University Hospital in Malmö, Sweden, in 2019. We reviewed the frequency and accuracy of PEX assessments in referrals and compliance of these referrals with the new guidelines. In addition, an optometrist’s ability to identify PEX was evaluated and compared to that of an ophthalmologist specialized in glaucoma. Patients... (More)

Purpose: To determine the frequency and accuracy of pseudoexfoliation syndrome (PEX) assessment in referrals from primary care optometrists before the new Swedish glaucoma guidelines were established, and to evaluate an optometrist’s ability to assess PEX. Patients and Methods: We studied PEX assessments in 95 referrals (95 patients,189 eyes) with elevated intraocular pressure (IOP) from optometrists to the Skåne University Hospital in Malmö, Sweden, in 2019. We reviewed the frequency and accuracy of PEX assessments in referrals and compliance of these referrals with the new guidelines. In addition, an optometrist’s ability to identify PEX was evaluated and compared to that of an ophthalmologist specialized in glaucoma. Patients referred were examined at the hospital for PEX, first by the study’s optometrist and then by the ophthalmologist. Results: PEX was present in 17% of the patients (16 patients, 19 eyes). The optometrist in this study positively assessed PEX in 12 of 19 eyes (63%) before dilatation and in 14 of 19 eyes (74%) after dilatation. Seven referrals included a PEX assessment (3 assessed PEX and 4 assessed non-PEX), all of which were confirmed as correct. Of the 16 patients with PEX, 13 did not undergo a PEX assessment before referral. According to the new Swedish guidelines, three of the 13 referrals would not have been accepted, meaning that two patients requiring treatment would have been missed, one with pseudoexfoliation glaucoma and one with ocular hypertension with PEX. Conclusion: Very few referrals from primary care optometrists included a PEX assessment (7%). According to the new guidelines, necessary referrals would therefore have been rejected. Still, the study’s optometrist detected PEX in the majority of patients. The risk of missing high risk patients requiring glaucoma treatment would be reduced if primary care optometrists assess PEX before referral.

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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ocular hypertension, open-angle glaucoma, referral guidelines, Sweden
in
Clinical Ophthalmology
volume
19
pages
8 pages
publisher
Dove Medical Press Ltd.
external identifiers
  • scopus:105001952956
  • pmid:40182624
ISSN
1177-5467
DOI
10.2147/OPTH.S505365
language
English
LU publication?
yes
id
b0b9bb4a-d0b0-42c3-8332-3893c0b9213a
date added to LUP
2025-09-03 12:26:32
date last changed
2025-09-04 03:00:02
@article{b0b9bb4a-d0b0-42c3-8332-3893c0b9213a,
  abstract     = {{<p>Purpose: To determine the frequency and accuracy of pseudoexfoliation syndrome (PEX) assessment in referrals from primary care optometrists before the new Swedish glaucoma guidelines were established, and to evaluate an optometrist’s ability to assess PEX. Patients and Methods: We studied PEX assessments in 95 referrals (95 patients,189 eyes) with elevated intraocular pressure (IOP) from optometrists to the Skåne University Hospital in Malmö, Sweden, in 2019. We reviewed the frequency and accuracy of PEX assessments in referrals and compliance of these referrals with the new guidelines. In addition, an optometrist’s ability to identify PEX was evaluated and compared to that of an ophthalmologist specialized in glaucoma. Patients referred were examined at the hospital for PEX, first by the study’s optometrist and then by the ophthalmologist. Results: PEX was present in 17% of the patients (16 patients, 19 eyes). The optometrist in this study positively assessed PEX in 12 of 19 eyes (63%) before dilatation and in 14 of 19 eyes (74%) after dilatation. Seven referrals included a PEX assessment (3 assessed PEX and 4 assessed non-PEX), all of which were confirmed as correct. Of the 16 patients with PEX, 13 did not undergo a PEX assessment before referral. According to the new Swedish guidelines, three of the 13 referrals would not have been accepted, meaning that two patients requiring treatment would have been missed, one with pseudoexfoliation glaucoma and one with ocular hypertension with PEX. Conclusion: Very few referrals from primary care optometrists included a PEX assessment (7%). According to the new guidelines, necessary referrals would therefore have been rejected. Still, the study’s optometrist detected PEX in the majority of patients. The risk of missing high risk patients requiring glaucoma treatment would be reduced if primary care optometrists assess PEX before referral.</p>}},
  author       = {{Landgren, Karin and Peters, Dorothea}},
  issn         = {{1177-5467}},
  keywords     = {{ocular hypertension; open-angle glaucoma; referral guidelines; Sweden}},
  language     = {{eng}},
  pages        = {{1111--1118}},
  publisher    = {{Dove Medical Press Ltd.}},
  series       = {{Clinical Ophthalmology}},
  title        = {{Optometrists’ Assessment of Pseudoexfoliation and Its Impact on Glaucoma Referrals}},
  url          = {{http://dx.doi.org/10.2147/OPTH.S505365}},
  doi          = {{10.2147/OPTH.S505365}},
  volume       = {{19}},
  year         = {{2025}},
}