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Influence of alcohol on several physiological functions and its reversibility : a surgical view

Tønnesen, Hanne LU (1992) In Acta Psychiatrica Scandinavica. Supplementum 86(Suppl 369). p.67-71
Abstract

Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol-induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further... (More)

Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol-induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further investigation is necessary to establish a clinical effect of preoperative withdrawal from alcohol.

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Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Alcoholism/immunology, Heart Rate/physiology, Homeostasis/physiology, Humans, Postoperative Complications, Stress, Physiological
in
Acta Psychiatrica Scandinavica. Supplementum
volume
86
issue
Suppl 369
pages
5 pages
publisher
Wiley-Blackwell
external identifiers
  • scopus:0026476299
  • pmid:1471555
ISSN
0065-1591
DOI
10.1111/j.1600-0447.1992.tb03318.x
language
English
LU publication?
no
id
b2524b97-a6a9-441a-a8ff-9508d66dd3d1
date added to LUP
2022-11-01 13:43:40
date last changed
2025-04-04 15:05:04
@article{b2524b97-a6a9-441a-a8ff-9508d66dd3d1,
  abstract     = {{<p>Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol-induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further investigation is necessary to establish a clinical effect of preoperative withdrawal from alcohol.</p>}},
  author       = {{Tønnesen, Hanne}},
  issn         = {{0065-1591}},
  keywords     = {{Alcoholism/immunology; Heart Rate/physiology; Homeostasis/physiology; Humans; Postoperative Complications; Stress, Physiological}},
  language     = {{eng}},
  number       = {{Suppl 369}},
  pages        = {{67--71}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Psychiatrica Scandinavica. Supplementum}},
  title        = {{Influence of alcohol on several physiological functions and its reversibility : a surgical view}},
  url          = {{http://dx.doi.org/10.1111/j.1600-0447.1992.tb03318.x}},
  doi          = {{10.1111/j.1600-0447.1992.tb03318.x}},
  volume       = {{86}},
  year         = {{1992}},
}