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Static and dynamic cardiac modelling : Initial strides and results towards a quantitatively accurate mechanical heart model

Constantinides, C. ; Aristokleous, N. LU orcid ; Johnson, G. A. and Perperides, D. (2010) 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 p.496-499
Abstract

Magnetic Resonance Imaging (MRI) has exhibited significant potential for quantifying cardiac function and dysfunction in the mouse. Recent advances in highresolution cardiac MR imaging techniques have contributed to the development of acquisition approaches that allow fast and accurate description of anatomic structures, and accurate surface and finite element (FE) mesh model constructions for study of global mechanical function in normal and transgenic mice. This study presents work in progress for construction of quantitatively accurate threedimensional (3D) and 4D dynamic surface and FE models of murine left ventricular (LV) muscle in C57BL/6J (n=10) mice. Constructed models are subsequently imported into commercial software packages... (More)

Magnetic Resonance Imaging (MRI) has exhibited significant potential for quantifying cardiac function and dysfunction in the mouse. Recent advances in highresolution cardiac MR imaging techniques have contributed to the development of acquisition approaches that allow fast and accurate description of anatomic structures, and accurate surface and finite element (FE) mesh model constructions for study of global mechanical function in normal and transgenic mice. This study presents work in progress for construction of quantitatively accurate threedimensional (3D) and 4D dynamic surface and FE models of murine left ventricular (LV) muscle in C57BL/6J (n=10) mice. Constructed models are subsequently imported into commercial software packages for the solution of the constitutive equations that characterize mechanical function, including computation of the stress and strain fields. They are further used with solid-free form fabrication processes to construct model-based material renditions of the human and mouse hearts.

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Please use this url to cite or link to this publication:
author
; ; and
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Cardiovascular system, Finite element methods, Image processing, Magnetic resonance imaging, Rapid prototyping
host publication
2010 7th IEEE International Symposium on Biomedical Imaging : From Nano to Macro, ISBI 2010 - Proceedings - From Nano to Macro, ISBI 2010 - Proceedings
article number
5490300
pages
4 pages
publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
conference name
7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
conference location
Rotterdam, Netherlands
conference dates
2010-04-14 - 2010-04-17
external identifiers
  • scopus:77955200051
ISBN
9781424441266
DOI
10.1109/ISBI.2010.5490300
language
English
LU publication?
no
id
b2805e04-b68d-499b-a189-5d7759dc7471
date added to LUP
2019-05-14 09:26:01
date last changed
2022-02-15 18:52:24
@inproceedings{b2805e04-b68d-499b-a189-5d7759dc7471,
  abstract     = {{<p>Magnetic Resonance Imaging (MRI) has exhibited significant potential for quantifying cardiac function and dysfunction in the mouse. Recent advances in highresolution cardiac MR imaging techniques have contributed to the development of acquisition approaches that allow fast and accurate description of anatomic structures, and accurate surface and finite element (FE) mesh model constructions for study of global mechanical function in normal and transgenic mice. This study presents work in progress for construction of quantitatively accurate threedimensional (3D) and 4D dynamic surface and FE models of murine left ventricular (LV) muscle in C57BL/6J (n=10) mice. Constructed models are subsequently imported into commercial software packages for the solution of the constitutive equations that characterize mechanical function, including computation of the stress and strain fields. They are further used with solid-free form fabrication processes to construct model-based material renditions of the human and mouse hearts.</p>}},
  author       = {{Constantinides, C. and Aristokleous, N. and Johnson, G. A. and Perperides, D.}},
  booktitle    = {{2010 7th IEEE International Symposium on Biomedical Imaging : From Nano to Macro, ISBI 2010 - Proceedings}},
  isbn         = {{9781424441266}},
  keywords     = {{Cardiovascular system; Finite element methods; Image processing; Magnetic resonance imaging; Rapid prototyping}},
  language     = {{eng}},
  month        = {{08}},
  pages        = {{496--499}},
  publisher    = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}},
  title        = {{Static and dynamic cardiac modelling : Initial strides and results towards a quantitatively accurate mechanical heart model}},
  url          = {{http://dx.doi.org/10.1109/ISBI.2010.5490300}},
  doi          = {{10.1109/ISBI.2010.5490300}},
  year         = {{2010}},
}