Follow-up after colorectal cancer surgery
(2003) In Acta Oncologica 42(8). p.816-826- Abstract
- Although most institutions offer some kind of follow-up to patients operated on for colorectal cancer, its value with respect to prolonged survival has been challenged. However, improved results of liver surgery and chemotherapy make it reasonable to assume that a follow-up programme leading to detection of more asymptomatic recurrences would result in improved survival. Liver metastases and extramural local recurrences are the most common secondary lesions and 5-year survival rates of about 30% are reported after radical resection. From these observations a survival benefit could be expected when follow-up is directed to these forms of recurrence. From six randomized studies, six comparative cohort studies and four meta-analyses it can be... (More)
- Although most institutions offer some kind of follow-up to patients operated on for colorectal cancer, its value with respect to prolonged survival has been challenged. However, improved results of liver surgery and chemotherapy make it reasonable to assume that a follow-up programme leading to detection of more asymptomatic recurrences would result in improved survival. Liver metastases and extramural local recurrences are the most common secondary lesions and 5-year survival rates of about 30% are reported after radical resection. From these observations a survival benefit could be expected when follow-up is directed to these forms of recurrence. From six randomized studies, six comparative cohort studies and four meta-analyses it can be concluded that an intensive follow-up programme results in more recurrences being resected for cure and about a 10% higher 5-year survival rate compared with less intensive or no follow-up. However, the differences in the follow-up protocols make it difficult to conclude how a follow-up programme should be designed. Liver imaging and carcinoembryonic antigen assay should probably be included, while the yield of frequent colonoscopies is small. A follow-up regimen based on these principles is suggested. Future studies should focus on which tests are the most cost-effective for follow- up after colorectal cancer resection. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/899654
- author
- Ohlsson, B and Pålsson, Birger LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Oncologica
- volume
- 42
- issue
- 8
- pages
- 816 - 826
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000187149200004
- pmid:14968942
- scopus:0347756678
- ISSN
- 1651-226X
- DOI
- 10.1080/02841860310019016
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200)
- id
- b3cafb83-65b0-4897-8dca-8f0d9cc3bfb9 (old id 899654)
- date added to LUP
- 2016-04-01 16:48:15
- date last changed
- 2022-03-07 08:25:42
@article{b3cafb83-65b0-4897-8dca-8f0d9cc3bfb9,
abstract = {{Although most institutions offer some kind of follow-up to patients operated on for colorectal cancer, its value with respect to prolonged survival has been challenged. However, improved results of liver surgery and chemotherapy make it reasonable to assume that a follow-up programme leading to detection of more asymptomatic recurrences would result in improved survival. Liver metastases and extramural local recurrences are the most common secondary lesions and 5-year survival rates of about 30% are reported after radical resection. From these observations a survival benefit could be expected when follow-up is directed to these forms of recurrence. From six randomized studies, six comparative cohort studies and four meta-analyses it can be concluded that an intensive follow-up programme results in more recurrences being resected for cure and about a 10% higher 5-year survival rate compared with less intensive or no follow-up. However, the differences in the follow-up protocols make it difficult to conclude how a follow-up programme should be designed. Liver imaging and carcinoembryonic antigen assay should probably be included, while the yield of frequent colonoscopies is small. A follow-up regimen based on these principles is suggested. Future studies should focus on which tests are the most cost-effective for follow- up after colorectal cancer resection.}},
author = {{Ohlsson, B and Pålsson, Birger}},
issn = {{1651-226X}},
language = {{eng}},
number = {{8}},
pages = {{816--826}},
publisher = {{Taylor & Francis}},
series = {{Acta Oncologica}},
title = {{Follow-up after colorectal cancer surgery}},
url = {{http://dx.doi.org/10.1080/02841860310019016}},
doi = {{10.1080/02841860310019016}},
volume = {{42}},
year = {{2003}},
}