Demonstration of a phospholipase A2 inhibitor in human plasma and in plasma from the European hedgehog (Erinaceus europaeus)
(1991) In International Journal of Biochemistry 23(3). p.287-292- Abstract
1. 1. Endogenous phospholipase A2 (PLA2) inhibitors in human plasma and in plasma from the hedgehog (Erinaceus europaeus) were demonstrated. 2. 2. The PLA2 activity increased 45-fold in human plasma when a PLA2 binding factor was removed. Furthermore, two peaks of PLA2 inhibitory activity were found after DEAE-chromatography. 3. 3. High levels of PLA2 inhibitory activity was found in plasma from the European hedgehog, E. europaeus. 4. 4. The molecular weight was estimated to 140,000. 5. 5. On DEAE-chromatography two peaks were found which were chromatographically similar to the PLA2 inhibitors in human plasma.
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- author
- Lindahl, Mats ; de Wit, Cynthia ; Weström, Björn LU ; von Schenck, Henning and Tagesson, Christer
- organization
- publishing date
- 1991
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Journal of Biochemistry
- volume
- 23
- issue
- 3
- pages
- 6 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:2044836
- scopus:0025924263
- ISSN
- 0020-711X
- DOI
- 10.1016/0020-711X(91)90108-Y
- language
- English
- LU publication?
- yes
- id
- b4024025-d6f5-4053-b8e7-7b71a112b29a
- date added to LUP
- 2024-12-05 15:21:08
- date last changed
- 2025-04-04 14:24:59
@article{b4024025-d6f5-4053-b8e7-7b71a112b29a, abstract = {{<p>1. 1. Endogenous phospholipase A<sub>2</sub> (PLA<sub>2</sub>) inhibitors in human plasma and in plasma from the hedgehog (Erinaceus europaeus) were demonstrated. 2. 2. The PLA<sub>2</sub> activity increased 45-fold in human plasma when a PLA<sub>2</sub> binding factor was removed. Furthermore, two peaks of PLA<sub>2</sub> inhibitory activity were found after DEAE-chromatography. 3. 3. High levels of PLA<sub>2</sub> inhibitory activity was found in plasma from the European hedgehog, E. europaeus. 4. 4. The molecular weight was estimated to 140,000. 5. 5. On DEAE-chromatography two peaks were found which were chromatographically similar to the PLA<sub>2</sub> inhibitors in human plasma.</p>}}, author = {{Lindahl, Mats and de Wit, Cynthia and Weström, Björn and von Schenck, Henning and Tagesson, Christer}}, issn = {{0020-711X}}, language = {{eng}}, number = {{3}}, pages = {{287--292}}, publisher = {{Elsevier}}, series = {{International Journal of Biochemistry}}, title = {{Demonstration of a phospholipase A<sub>2</sub> inhibitor in human plasma and in plasma from the European hedgehog (Erinaceus europaeus)}}, url = {{http://dx.doi.org/10.1016/0020-711X(91)90108-Y}}, doi = {{10.1016/0020-711X(91)90108-Y}}, volume = {{23}}, year = {{1991}}, }