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Priorities in Cardio-Oncology Basic and Translational Science : GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review

Salloum, Fadi N. ; Tocchetti, Carlo G. ; Ameri, Pietro ; Ardehali, Hossein ; Asnani, Aarti ; de Boer, Rudolf A. ; Burridge, Paul ; Cabrera, José Ángel ; de Castro, Javier and Córdoba, Raúl , et al. (2023) In JACC: CardioOncology 5(6). p.715-731
Abstract

Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care. We acknowledge that there are many... (More)

Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care. We acknowledge that there are many additional therapies that are of significance but were not topics of discussion at this symposium. We hope that through this symposium-based review we can highlight the knowledge gaps and clinical priorities to inform the design of future studies that aim to prevent and mitigate cardiovascular disease in cancer patients and survivors.

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author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
anthracyclines, basic research, cancer, cardiac arrhythmias, cardio-oncology, cardiotoxicity, chemotherapy, immunotherapy, translational research
in
JACC: CardioOncology
volume
5
issue
6
pages
715 - 731
publisher
Elsevier
external identifiers
  • pmid:38205010
  • scopus:85174025308
ISSN
2666-0873
DOI
10.1016/j.jaccao.2023.08.003
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2023 The Authors
id
b41de53b-a4ae-43f4-a0b1-bab9ca23cce1
date added to LUP
2023-11-05 13:47:56
date last changed
2024-04-19 04:36:10
@article{b41de53b-a4ae-43f4-a0b1-bab9ca23cce1,
  abstract     = {{<p>Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care. We acknowledge that there are many additional therapies that are of significance but were not topics of discussion at this symposium. We hope that through this symposium-based review we can highlight the knowledge gaps and clinical priorities to inform the design of future studies that aim to prevent and mitigate cardiovascular disease in cancer patients and survivors.</p>}},
  author       = {{Salloum, Fadi N. and Tocchetti, Carlo G. and Ameri, Pietro and Ardehali, Hossein and Asnani, Aarti and de Boer, Rudolf A. and Burridge, Paul and Cabrera, José Ángel and de Castro, Javier and Córdoba, Raúl and Costa, Ambra and Dent, Susan and Engelbertsen, Daniel and Fernández-Velasco, María and Fradley, Mike and Fuster, José J. and Galán-Arriola, Carlos and García-Lunar, Inés and Ghigo, Alessandra and González-Neira, Anna and Hirsch, Emilio and Ibáñez, Borja and Kitsis, Rickard N. and Konety, Suma and Lyon, Alexander R. and Martin, Pilar and Mauro, Adolfo G. and Mazo Vega, Manuel M. and Meijers, Wouter C. and Neilan, Tomas G. and Rassaf, Tienush and Ricke-Hoch, Melanie and Sepulveda, Pilar and Thavendiranathan, Paaladinesh and van der Meer, Peter and Fuster, Valentin and Ky, Bonnie and López-Fernández, Teresa}},
  issn         = {{2666-0873}},
  keywords     = {{anthracyclines; basic research; cancer; cardiac arrhythmias; cardio-oncology; cardiotoxicity; chemotherapy; immunotherapy; translational research}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{715--731}},
  publisher    = {{Elsevier}},
  series       = {{JACC: CardioOncology}},
  title        = {{Priorities in Cardio-Oncology Basic and Translational Science : GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review}},
  url          = {{http://dx.doi.org/10.1016/j.jaccao.2023.08.003}},
  doi          = {{10.1016/j.jaccao.2023.08.003}},
  volume       = {{5}},
  year         = {{2023}},
}