Study II: Mechanoreceptive sensation is of increased importance for human postural control under alcohol intoxication.
Modig, Fredrik LU ; Patel, Mitesh LU ; Magnusson, Måns LU
and Fransson, Per-Anders
LU
(2012)
In Gait & Posture
35(3).
p.419-427
- Abstract
- Standing postural stability relies on input from visual, vestibular, proprioceptive and mechanoreceptive sensors. When the information from any of these sensors is unavailable or disrupted, the central nervous system maintains postural stability by relying more on the contribution from the reliable sensors, termed sensory re-weighting. Alcohol intoxication is known to affect the integrity of the vestibular and visual systems. The aim was to assess how mechanoreceptive sensory information contributed to postural stability at 0.00% (i.e. sober), 0.06% and 0.10% blood alcohol concentration (BAC) in 25 healthy subjects (mean age 25.1 years). The subjects were assessed with eyes closed and eyes open under quiet standing and while standing was... (More)
- Standing postural stability relies on input from visual, vestibular, proprioceptive and mechanoreceptive sensors. When the information from any of these sensors is unavailable or disrupted, the central nervous system maintains postural stability by relying more on the contribution from the reliable sensors, termed sensory re-weighting. Alcohol intoxication is known to affect the integrity of the vestibular and visual systems. The aim was to assess how mechanoreceptive sensory information contributed to postural stability at 0.00% (i.e. sober), 0.06% and 0.10% blood alcohol concentration (BAC) in 25 healthy subjects (mean age 25.1 years). The subjects were assessed with eyes closed and eyes open under quiet standing and while standing was perturbed by repeated, random-length, vibratory stimulation of the calf muscles. Plantar cutaneous mechanoreceptive sensation was assessed for both receptor types: slowly adapting (tactile sensitivity) and rapidly adapting (vibration perception). The correlation between recorded torque variance and the sensation from both mechanoreceptor types was calculated. The recorded stability during alcohol intoxication was significantly influenced by both the tactile sensation and vibration perception of the subjects. Moreover, the study revealed a fluctuating association between the subjects' vibration perception and torque variance during balance perturbations, which was significantly influenced by the level of alcohol intoxication, vision and adaptation. Hence, one's ability to handle balance perturbations under the influence of alcohol is strongly dependent on accurate mechanoreceptive sensation and efficient sensory re-weighting. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2273464
- author
- Modig, Fredrik
LU
; Patel, Mitesh
LU
; Magnusson, Måns
LU
and Fransson, Per-Anders
LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Gait & Posture
- volume
- 35
- issue
- 3
- pages
- 419 - 427
- publisher
- Elsevier
- external identifiers
-
- wos:000302453200012
- pmid:22206781
- scopus:84858000884
- pmid:22206781
- ISSN
- 1879-2219
- DOI
- 10.1016/j.gaitpost.2011.11.001
- language
- English
- LU publication?
- yes
- id
- b505f1eb-10b2-4678-aad2-fd1190d42524 (old id 2273464)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22206781?dopt=Abstract
- date added to LUP
- 2016-04-04 09:30:49
- date last changed
- 2024-01-12 14:33:35
@article{b505f1eb-10b2-4678-aad2-fd1190d42524,
abstract = {{Standing postural stability relies on input from visual, vestibular, proprioceptive and mechanoreceptive sensors. When the information from any of these sensors is unavailable or disrupted, the central nervous system maintains postural stability by relying more on the contribution from the reliable sensors, termed sensory re-weighting. Alcohol intoxication is known to affect the integrity of the vestibular and visual systems. The aim was to assess how mechanoreceptive sensory information contributed to postural stability at 0.00% (i.e. sober), 0.06% and 0.10% blood alcohol concentration (BAC) in 25 healthy subjects (mean age 25.1 years). The subjects were assessed with eyes closed and eyes open under quiet standing and while standing was perturbed by repeated, random-length, vibratory stimulation of the calf muscles. Plantar cutaneous mechanoreceptive sensation was assessed for both receptor types: slowly adapting (tactile sensitivity) and rapidly adapting (vibration perception). The correlation between recorded torque variance and the sensation from both mechanoreceptor types was calculated. The recorded stability during alcohol intoxication was significantly influenced by both the tactile sensation and vibration perception of the subjects. Moreover, the study revealed a fluctuating association between the subjects' vibration perception and torque variance during balance perturbations, which was significantly influenced by the level of alcohol intoxication, vision and adaptation. Hence, one's ability to handle balance perturbations under the influence of alcohol is strongly dependent on accurate mechanoreceptive sensation and efficient sensory re-weighting.}},
author = {{Modig, Fredrik and Patel, Mitesh and Magnusson, Måns and Fransson, Per-Anders}},
issn = {{1879-2219}},
language = {{eng}},
number = {{3}},
pages = {{419--427}},
publisher = {{Elsevier}},
series = {{Gait & Posture}},
title = {{Study II: Mechanoreceptive sensation is of increased importance for human postural control under alcohol intoxication.}},
url = {{http://dx.doi.org/10.1016/j.gaitpost.2011.11.001}},
doi = {{10.1016/j.gaitpost.2011.11.001}},
volume = {{35}},
year = {{2012}},
}