Follow-up of acute pyelonephritis in children by Tc-99m DMSA scintigraphy - Quantitative and qualitative assessment
(2001) In Clinical Nuclear Medicine 26(5). p.423-432- Abstract
- Purpose: The author's goal was to create a system to identify children at risk for development of progressive renal damage, Methods: Thirty-four children were examined with Tc-99m DMSA scintigraphy in the acute stage of an initial episode of pyelonephritis, after 6 months, and again after 1 year, The scintigraphic findings were correlated with clinical and laboratory data, Results: All children had parenchymal defects in the acute stage: 93% of the kidneys and 85% bilaterally, After 6 months, the defects had diminished or disappeared in 66% of the kidneys, New defects appeared in 22%, At 1 year, no further improvement was seen in the kidneys, with an improved or unchanged pattern at 6 months, New defects appeared in 34%, Mean kidney... (More)
- Purpose: The author's goal was to create a system to identify children at risk for development of progressive renal damage, Methods: Thirty-four children were examined with Tc-99m DMSA scintigraphy in the acute stage of an initial episode of pyelonephritis, after 6 months, and again after 1 year, The scintigraphic findings were correlated with clinical and laboratory data, Results: All children had parenchymal defects in the acute stage: 93% of the kidneys and 85% bilaterally, After 6 months, the defects had diminished or disappeared in 66% of the kidneys, New defects appeared in 22%, At 1 year, no further improvement was seen in the kidneys, with an improved or unchanged pattern at 6 months, New defects appeared in 34%, Mean kidney activity uptake expressed as the percentage of administered dose (KU/AD), was low in the acute stage, increased at 6 months, with no further significant increase at 1 year, Eighty-three percent of children with urine cultures growing greater than or equal to 10(4) bacteria/ml at follow-up had decreased KU/AD values, whereas all children with urine cultures growing < 10(4) bacteria/ml had increased KU/AD values. Conclusions: Quantitative assessment increases the sensitivity of Tc-99m DMSA scintigraphy. Follow-up with this method makes it possible to identify the children with decreasing renal tubular function who may be at risk for progressive renal damage, Moderate bacteria of 104 bacteria/ml urine is associated with deterioration of renal tubular function. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1119283
- author
- Wallin, Lena ; Helin, Ingemar and Bajc, Marika LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acute Pyelonephritis, Bacteruria, Tc-99m DMSA Scintigraphy
- in
- Clinical Nuclear Medicine
- volume
- 26
- issue
- 5
- pages
- 423 - 432
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000168298400010
- scopus:0035028898
- ISSN
- 0363-9762
- language
- English
- LU publication?
- yes
- id
- b573f1ac-3cd4-4de9-8544-0aba7a606830 (old id 1119283)
- date added to LUP
- 2016-04-01 12:09:48
- date last changed
- 2022-01-26 23:41:54
@article{b573f1ac-3cd4-4de9-8544-0aba7a606830, abstract = {{Purpose: The author's goal was to create a system to identify children at risk for development of progressive renal damage, Methods: Thirty-four children were examined with Tc-99m DMSA scintigraphy in the acute stage of an initial episode of pyelonephritis, after 6 months, and again after 1 year, The scintigraphic findings were correlated with clinical and laboratory data, Results: All children had parenchymal defects in the acute stage: 93% of the kidneys and 85% bilaterally, After 6 months, the defects had diminished or disappeared in 66% of the kidneys, New defects appeared in 22%, At 1 year, no further improvement was seen in the kidneys, with an improved or unchanged pattern at 6 months, New defects appeared in 34%, Mean kidney activity uptake expressed as the percentage of administered dose (KU/AD), was low in the acute stage, increased at 6 months, with no further significant increase at 1 year, Eighty-three percent of children with urine cultures growing greater than or equal to 10(4) bacteria/ml at follow-up had decreased KU/AD values, whereas all children with urine cultures growing < 10(4) bacteria/ml had increased KU/AD values. Conclusions: Quantitative assessment increases the sensitivity of Tc-99m DMSA scintigraphy. Follow-up with this method makes it possible to identify the children with decreasing renal tubular function who may be at risk for progressive renal damage, Moderate bacteria of 104 bacteria/ml urine is associated with deterioration of renal tubular function.}}, author = {{Wallin, Lena and Helin, Ingemar and Bajc, Marika}}, issn = {{0363-9762}}, keywords = {{Acute Pyelonephritis; Bacteruria; Tc-99m DMSA Scintigraphy}}, language = {{eng}}, number = {{5}}, pages = {{423--432}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Clinical Nuclear Medicine}}, title = {{Follow-up of acute pyelonephritis in children by Tc-99m DMSA scintigraphy - Quantitative and qualitative assessment}}, volume = {{26}}, year = {{2001}}, }