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Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year

Roemer, Frank W. LU ; Kwoh, C. Kent; Hannon, Michael J.; Hunter, David J.; Eckstein, Felix; Grago, Jason; Boudreau, Robert M.; Englund, Martin LU and Guermazi, Ali (2017) In European Radiology 27(1). p.404-413
Abstract

Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 % underwent partial meniscectomy during the year prior to the case-defining visit,... (More)

Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 % underwent partial meniscectomy during the year prior to the case-defining visit, compared with none of the knees that did not develop ROA. All (n = 31) knees that had partial meniscectomy and 58.9 % (n = 165) of the knees with prevalent meniscal damage developed ROA (OR = 2.51, 95 % CI [1.73, 3.64]). In knees that developed ROA, partial meniscectomy was associated with an increased risk of worsening cartilage damage (OR = 4.51, 95 % CI [1.53, 13.33]). Conclusions: The probability of having had partial meniscectomy was higher in knees that developed ROA. When looking only at knees that developed ROA, partial meniscectomy was associated with greater risk of worsening cartilage damage. Key Points: • Partial meniscectomy is a controversial treatment option for degenerative meniscal tears. • Partial meniscectomy is strongly associated with incident osteoarthritis within 1 year. • Partial meniscectomy is associated with increased risk of worsening cartilage damage.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cartilage loss, Meniscus, MRI, Osteoarthritis, Partial meniscectomy
in
European Radiology
volume
27
issue
1
pages
10 pages
publisher
Springer
external identifiers
  • scopus:84998610635
  • wos:000389350100045
ISSN
0938-7994
DOI
10.1007/s00330-016-4361-z
language
English
LU publication?
yes
id
b5d46e62-dab5-4269-a786-2b58af834bbf
date added to LUP
2016-12-28 13:55:28
date last changed
2018-05-06 04:29:18
@article{b5d46e62-dab5-4269-a786-2b58af834bbf,
  abstract     = {<p>Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system. Conditional logistic regression was applied to estimate risk of incident ROA. Logistic regression was used to assess the risk of worsening cartilage damage in knees with partial meniscectomy that developed ROA. Results: In the group with incident ROA, 4.4 % underwent partial meniscectomy during the year prior to the case-defining visit, compared with none of the knees that did not develop ROA. All (n = 31) knees that had partial meniscectomy and 58.9 % (n = 165) of the knees with prevalent meniscal damage developed ROA (OR = 2.51, 95 % CI [1.73, 3.64]). In knees that developed ROA, partial meniscectomy was associated with an increased risk of worsening cartilage damage (OR = 4.51, 95 % CI [1.53, 13.33]). Conclusions: The probability of having had partial meniscectomy was higher in knees that developed ROA. When looking only at knees that developed ROA, partial meniscectomy was associated with greater risk of worsening cartilage damage. Key Points: • Partial meniscectomy is a controversial treatment option for degenerative meniscal tears. • Partial meniscectomy is strongly associated with incident osteoarthritis within 1 year. • Partial meniscectomy is associated with increased risk of worsening cartilage damage.</p>},
  author       = {Roemer, Frank W. and Kwoh, C. Kent and Hannon, Michael J. and Hunter, David J. and Eckstein, Felix and Grago, Jason and Boudreau, Robert M. and Englund, Martin and Guermazi, Ali},
  issn         = {0938-7994},
  keyword      = {Cartilage loss,Meniscus,MRI,Osteoarthritis,Partial meniscectomy},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {404--413},
  publisher    = {Springer},
  series       = {European Radiology},
  title        = {Partial meniscectomy is associated with increased risk of incident radiographic osteoarthritis and worsening cartilage damage in the following year},
  url          = {http://dx.doi.org/10.1007/s00330-016-4361-z},
  volume       = {27},
  year         = {2017},
}