Low incidence of toxoplasma infection during pregnancy and in newborn in Sweden
(2001) In Epidemiology and Infection 127(1). p.121-127- Abstract
- To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of
primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978
children born in two regions in Sweden was determined. Women possibly infected during
pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of
the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal
samples to detect women who acquired infection during pregnancy and follow up of their
children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.
The birth prevalence of congenital toxoplasmosis was 0±73}10000... (More) - To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of
primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978
children born in two regions in Sweden was determined. Women possibly infected during
pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of
the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal
samples to detect women who acquired infection during pregnancy and follow up of their
children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.
The birth prevalence of congenital toxoplasmosis was 0±73}10000 (95% CI
0±15±2±14) (3}40978).
The incidence of primary infection during pregnancy was 5±1}10000 (95% CI 2±6±8±9)
susceptible pregnant women. The seroprevalence in the southern part was 25±7% and in the
Stockholm area 14±0%.
The incidence of infection during pregnancy was low, as the birth prevalence of congenital
toxoplasmosis. Neonatal screening warrants consideration in view of the low cost and
feasibility. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1122626
- author
- Evengård, B ; Pettersson, K ; Engman, ML ; Wiklund, Sven LU ; Ivarsson, SA ; Teär-Fahnehjelm, K ; Forsgren, M ; Gilbert, R and Malm, G
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Epidemiology and Infection
- volume
- 127
- issue
- 1
- pages
- 121 - 127
- publisher
- Cambridge University Press
- external identifiers
-
- scopus:0034839540
- ISSN
- 0950-2688
- DOI
- 10.1017/S0950268801005775
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Paediatric Endocrinology Research Group (013243010)
- id
- b65ce276-14ce-4884-9841-bb44f872a0da (old id 1122626)
- date added to LUP
- 2016-04-01 11:57:31
- date last changed
- 2022-03-28 18:12:09
@article{b65ce276-14ce-4884-9841-bb44f872a0da,
abstract = {{To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of<br/><br>
primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978<br/><br>
children born in two regions in Sweden was determined. Women possibly infected during<br/><br>
pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of<br/><br>
the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal<br/><br>
samples to detect women who acquired infection during pregnancy and follow up of their<br/><br>
children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.<br/><br>
The birth prevalence of congenital toxoplasmosis was 0±73}10000 (95% CI<br/><br>
0±15±2±14) (3}40978).<br/><br>
The incidence of primary infection during pregnancy was 5±1}10000 (95% CI 2±6±8±9)<br/><br>
susceptible pregnant women. The seroprevalence in the southern part was 25±7% and in the<br/><br>
Stockholm area 14±0%.<br/><br>
The incidence of infection during pregnancy was low, as the birth prevalence of congenital<br/><br>
toxoplasmosis. Neonatal screening warrants consideration in view of the low cost and<br/><br>
feasibility.}},
author = {{Evengård, B and Pettersson, K and Engman, ML and Wiklund, Sven and Ivarsson, SA and Teär-Fahnehjelm, K and Forsgren, M and Gilbert, R and Malm, G}},
issn = {{0950-2688}},
language = {{eng}},
number = {{1}},
pages = {{121--127}},
publisher = {{Cambridge University Press}},
series = {{Epidemiology and Infection}},
title = {{Low incidence of toxoplasma infection during pregnancy and in newborn in Sweden}},
url = {{http://dx.doi.org/10.1017/S0950268801005775}},
doi = {{10.1017/S0950268801005775}},
volume = {{127}},
year = {{2001}},
}