Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates
(1991) In Genomics 11(4). p.4-920- Abstract
- The gene for beta-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10. The coding nucleotides of the human gene are separated into four exons by relatively large introns. A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3965204
- author
- Ulvsbäck, M. ; Spurr, N. K. and Lundwall, Åke LU
- organization
- publishing date
- 1991
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- *Prostatic Secretory Proteins, Molecular Sequence Data, Humans, Dna, Molecular, Cloning, Pair 10, Human, *Chromosomes, Chromosome Mapping, Southern, Blotting, Animals, Base Sequence, Proteins/*genetics, Research Support, Non-U.S. Gov't, Restriction Mapping, Semen/*metabolism, Seminal Plasma Proteins, Vertebrates/genetics
- in
- Genomics
- volume
- 11
- issue
- 4
- pages
- 4 - 920
- publisher
- Academic Press
- external identifiers
-
- scopus:0026353104
- ISSN
- 1089-8646
- language
- English
- LU publication?
- yes
- additional info
- 4
- id
- b73e2116-6113-4890-a2ce-0aa61c8837c8 (old id 3965204)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1783399
- date added to LUP
- 2016-04-04 14:36:45
- date last changed
- 2021-01-03 07:29:55
@article{b73e2116-6113-4890-a2ce-0aa61c8837c8, abstract = {{The gene for beta-microseminoprotein MSMB has been studied by DNA hybridization and molecular cloning techniques. Comparative analysis of restriction endonuclease digests of the cloned gene and of leukocyte DNA strongly suggested that the gene is present in a single copy in the haploid human genome. By Southern blot analysis of DNA from somatic cell hybrids, the gene was assigned to chromosome 10. The coding nucleotides of the human gene are separated into four exons by relatively large introns. A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency.}}, author = {{Ulvsbäck, M. and Spurr, N. K. and Lundwall, Åke}}, issn = {{1089-8646}}, keywords = {{*Prostatic Secretory Proteins; Molecular Sequence Data; Humans; Dna; Molecular; Cloning; Pair 10; Human; *Chromosomes; Chromosome Mapping; Southern; Blotting; Animals; Base Sequence; Proteins/*genetics; Research Support; Non-U.S. Gov't; Restriction Mapping; Semen/*metabolism; Seminal Plasma Proteins; Vertebrates/genetics}}, language = {{eng}}, number = {{4}}, pages = {{4--920}}, publisher = {{Academic Press}}, series = {{Genomics}}, title = {{Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1783399}}, volume = {{11}}, year = {{1991}}, }