Surgery for primary ventral hernias and risk of postoperative pain, nausea : a population-based register study
Ali, Fathalla ; Wallin, Göran ; Wahlin, Rebecka Rubenson ; Montgomery, Agneta LU ; Rogmark, Peder LU
and Sandblom, Gabriel
(2025)
In Hernia
29(1).
- Abstract
Purpose: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias. Method: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register. Results: Altogether 2064 open ventral hernia repairs were registered, including 816 (39.5%) performed on women. Of these, 91 (4.4%) were registered to suffer postoperative nausea or vomiting (PONV) and 403 (19.5%) postoperative pain (PP). In both univariable and multivariable logistic regression analyses, significant predictors of postoperative nausea and pain included... (More)
Purpose: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias. Method: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register. Results: Altogether 2064 open ventral hernia repairs were registered, including 816 (39.5%) performed on women. Of these, 91 (4.4%) were registered to suffer postoperative nausea or vomiting (PONV) and 403 (19.5%) postoperative pain (PP). In both univariable and multivariable logistic regression analyses, significant predictors of postoperative nausea and pain included male gender, which was associated with lower odds of both postoperative nausea (multivariable OR: 0.30, 95% CI: 0.18–0.49, P < 0.001) and postoperative pain (multivariable OR: 0.60, 95% CI: 0.44–0.83, P = 0.002). Additional predictors of postoperative nausea included emergency surgery (multivariable OR: 4.08, 95% CI: 1.10-15.08, P = 0.035), operative time > 40 min (multivariable OR: 4.15, 95% CI: 2.24–7.69, P < 0.001). Conversely total intravenous anesthesia was associated with lower incidence of PONV (multivariable OR: 0.40, 95% CI: 0.22–0.74, P = 0.003). Other factors, such as age, BMI, smoking status, ASA classification, hernia size, surgery type, operative time, and anesthesia type, were not significantly associated with postoperative pain after adjusting for other variables. Conclusion: Postoperative nausea and vomiting (PONV) are significantly reduced with total intravenous anesthesia (TIVA) compared to inhalation anesthesia, with no notable difference in postoperative pain between the two methods.
(Less)
- author
- Ali, Fathalla
; Wallin, Göran
; Wahlin, Rebecka Rubenson
; Montgomery, Agneta
LU
; Rogmark, Peder
LU
and Sandblom, Gabriel
- organization
- publishing date
- 2025
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- General anesthesia, Inhalation anesthesia, Postoperative pain and nausea/vomiting, Primary ventral hernia, Umbilical hernia
- in
- Hernia
- volume
- 29
- issue
- 1
- article number
- 68
- publisher
- Springer
- external identifiers
-
- scopus:85215759588
- pmid:39812906
- ISSN
- 1265-4906
- DOI
- 10.1007/s10029-025-03256-4
- language
- English
- LU publication?
- yes
- id
- b84f584a-c061-48b8-b097-ba565f59f14a
- date added to LUP
- 2025-05-28 09:18:35
- date last changed
- 2025-12-11 03:11:56
@article{b84f584a-c061-48b8-b097-ba565f59f14a,
abstract = {{<p>Purpose: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias. Method: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register. Results: Altogether 2064 open ventral hernia repairs were registered, including 816 (39.5%) performed on women. Of these, 91 (4.4%) were registered to suffer postoperative nausea or vomiting (PONV) and 403 (19.5%) postoperative pain (PP). In both univariable and multivariable logistic regression analyses, significant predictors of postoperative nausea and pain included male gender, which was associated with lower odds of both postoperative nausea (multivariable OR: 0.30, 95% CI: 0.18–0.49, P < 0.001) and postoperative pain (multivariable OR: 0.60, 95% CI: 0.44–0.83, P = 0.002). Additional predictors of postoperative nausea included emergency surgery (multivariable OR: 4.08, 95% CI: 1.10-15.08, P = 0.035), operative time > 40 min (multivariable OR: 4.15, 95% CI: 2.24–7.69, P < 0.001). Conversely total intravenous anesthesia was associated with lower incidence of PONV (multivariable OR: 0.40, 95% CI: 0.22–0.74, P = 0.003). Other factors, such as age, BMI, smoking status, ASA classification, hernia size, surgery type, operative time, and anesthesia type, were not significantly associated with postoperative pain after adjusting for other variables. Conclusion: Postoperative nausea and vomiting (PONV) are significantly reduced with total intravenous anesthesia (TIVA) compared to inhalation anesthesia, with no notable difference in postoperative pain between the two methods.</p>}},
author = {{Ali, Fathalla and Wallin, Göran and Wahlin, Rebecka Rubenson and Montgomery, Agneta and Rogmark, Peder and Sandblom, Gabriel}},
issn = {{1265-4906}},
keywords = {{General anesthesia; Inhalation anesthesia; Postoperative pain and nausea/vomiting; Primary ventral hernia; Umbilical hernia}},
language = {{eng}},
number = {{1}},
publisher = {{Springer}},
series = {{Hernia}},
title = {{Surgery for primary ventral hernias and risk of postoperative pain, nausea : a population-based register study}},
url = {{http://dx.doi.org/10.1007/s10029-025-03256-4}},
doi = {{10.1007/s10029-025-03256-4}},
volume = {{29}},
year = {{2025}},
}