Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Clarification and Modification of the International Contact Dermatitis Research Group Classification of Patch Test Reactions on Behalf of the International Contact Dermatitis Research Group

Bruze, Magnus LU and Svedman, Cecilia LU (2025) In Dermatitis
Abstract

The first ICDRG (International Contact Dermatitis Research Group) classification of patch test reactions was published in 1970. With this classification, many weak reactions were classified as allergic reactions. A second classification was therefore implemented one decade later on behalf of the ICDRG and the North American Contact Dermatitis Group. This classification was adopted by the European Society of Contact Dermatitis. Evaluation of the significance of the results of various studies on patch test reading demonstrated that a new ICDRG classification of patch test reactions was needed. A classification system should not be based on the exclusive presence/absence of papules and vesicles, i.e., the words “possibly papules/vesicles”... (More)

The first ICDRG (International Contact Dermatitis Research Group) classification of patch test reactions was published in 1970. With this classification, many weak reactions were classified as allergic reactions. A second classification was therefore implemented one decade later on behalf of the ICDRG and the North American Contact Dermatitis Group. This classification was adopted by the European Society of Contact Dermatitis. Evaluation of the significance of the results of various studies on patch test reading demonstrated that a new ICDRG classification of patch test reactions was needed. A classification system should not be based on the exclusive presence/absence of papules and vesicles, i.e., the words “possibly papules/vesicles” allow for the unavoidable variation in reading among experts. Dermatologists are not reading patch test reactions in a uniform way due to lack of a clear definition of the threshold between weak allergic and doubtful reactions. A new ICDRG classification with clarifications and modifications of the old one is presented.

(Less)
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
allergic contact dermatitis, contact allergy, delayed hypersensitivity, epicutaneous test
in
Dermatitis
publisher
Mary Ann Liebert, Inc.
external identifiers
  • pmid:39773000
  • scopus:85215680257
ISSN
1710-3568
DOI
10.1089/derm.2024.0365
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2025 American Contact Dermatitis Society. All Rights Reserved.
id
b9264f6b-09e6-4484-b77c-91d81cad74a7
date added to LUP
2025-04-23 13:43:57
date last changed
2025-07-02 20:19:51
@article{b9264f6b-09e6-4484-b77c-91d81cad74a7,
  abstract     = {{<p>The first ICDRG (International Contact Dermatitis Research Group) classification of patch test reactions was published in 1970. With this classification, many weak reactions were classified as allergic reactions. A second classification was therefore implemented one decade later on behalf of the ICDRG and the North American Contact Dermatitis Group. This classification was adopted by the European Society of Contact Dermatitis. Evaluation of the significance of the results of various studies on patch test reading demonstrated that a new ICDRG classification of patch test reactions was needed. A classification system should not be based on the exclusive presence/absence of papules and vesicles, i.e., the words “possibly papules/vesicles” allow for the unavoidable variation in reading among experts. Dermatologists are not reading patch test reactions in a uniform way due to lack of a clear definition of the threshold between weak allergic and doubtful reactions. A new ICDRG classification with clarifications and modifications of the old one is presented.</p>}},
  author       = {{Bruze, Magnus and Svedman, Cecilia}},
  issn         = {{1710-3568}},
  keywords     = {{allergic contact dermatitis; contact allergy; delayed hypersensitivity; epicutaneous test}},
  language     = {{eng}},
  publisher    = {{Mary Ann Liebert, Inc.}},
  series       = {{Dermatitis}},
  title        = {{Clarification and Modification of the International Contact Dermatitis Research Group Classification of Patch Test Reactions on Behalf of the International Contact Dermatitis Research Group}},
  url          = {{http://dx.doi.org/10.1089/derm.2024.0365}},
  doi          = {{10.1089/derm.2024.0365}},
  year         = {{2025}},
}