Development of a Divergent Route to Erythrina Alkaloids
Clementson, Sebastian LU
; Jessing, Mikkel
; Vital, Paulo J.
and Kristensen, Jesper L.
(2020)
In Synlett
31(4).
p.327-333
- Abstract
Erythrina alkaloids were identified at the end of the 19th century and today, more than 100 members of the erythrinane family have been isolated. They are characterized by a unique tetracyclic, α-tertiary spiroamine scaffold. Herein we detail our efforts towards the development of a divergent enantioselective synthesis of (+)-dihydro-β-erythroidine (DHβE) - one of the most prominent members of this intriguing family of natural products.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/b9a7ff0e-7622-4b53-80ca-4ab2c6ae90ca
- author
- Clementson, Sebastian
LU
; Jessing, Mikkel
; Vital, Paulo J.
and Kristensen, Jesper L.
- publishing date
- 2020-03-03
- type
- Contribution to journal
- publication status
- published
- keywords
- asymmetric allylic alkylation, decarboxylative cross coupling, Erythrina alkaloids, ring closing metathesis, spiroamine, total synthesis
- in
- Synlett
- volume
- 31
- issue
- 4
- article number
- st-2019-a0679-a
- pages
- 7 pages
- publisher
- Georg Thieme Verlag
- external identifiers
-
- scopus:85079828311
- ISSN
- 0936-5214
- DOI
- 10.1055/s-0039-1690792
- language
- English
- LU publication?
- no
- id
- b9a7ff0e-7622-4b53-80ca-4ab2c6ae90ca
- date added to LUP
- 2025-08-06 19:53:20
- date last changed
- 2025-09-01 11:22:49
@article{b9a7ff0e-7622-4b53-80ca-4ab2c6ae90ca,
abstract = {{<p>Erythrina alkaloids were identified at the end of the 19th century and today, more than 100 members of the erythrinane family have been isolated. They are characterized by a unique tetracyclic, α-tertiary spiroamine scaffold. Herein we detail our efforts towards the development of a divergent enantioselective synthesis of (+)-dihydro-β-erythroidine (DHβE) - one of the most prominent members of this intriguing family of natural products.</p>}},
author = {{Clementson, Sebastian and Jessing, Mikkel and Vital, Paulo J. and Kristensen, Jesper L.}},
issn = {{0936-5214}},
keywords = {{asymmetric allylic alkylation; decarboxylative cross coupling; Erythrina alkaloids; ring closing metathesis; spiroamine; total synthesis}},
language = {{eng}},
month = {{03}},
number = {{4}},
pages = {{327--333}},
publisher = {{Georg Thieme Verlag}},
series = {{Synlett}},
title = {{Development of a Divergent Route to Erythrina Alkaloids}},
url = {{http://dx.doi.org/10.1055/s-0039-1690792}},
doi = {{10.1055/s-0039-1690792}},
volume = {{31}},
year = {{2020}},
}