Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Wound dehiscence rates decreased in reconstructive surgery of anorectal malformations after introduction of a standardized postoperative treatment program

Tofft, Louise LU orcid ; Granéli, Christina LU ; Hagelsteen, Kristine LU orcid ; Wester Fleur, Matilda LU orcid and Stenström, Pernilla LU orcid (2025) In World Journal of Pediatric Surgery 8(3).
Abstract

Background Wound dehiscence is a known complication after anorectal malformations (ARMs) surgery. The aim was to evaluate if a standardized post-posterior sagittal anorectoplasty (PSARP) treatment program decreased wound dehiscence rates. Methods Wound dehiscence rates within 30 days post-PSARP were compared in a case-control single-center study between patients with a standardized post-PSARP treatment 2017-2023, and a cohort with a non-standardized management 2001-2016. The standardized post-PSARP program comprised a minimum of 3 days of: intravenous antibiotics imipenem+cilastatin (with optional subsequent oral amoxicillin+clavulanic acid+metronidazole), fasting after primary PSARP (no stoma), urinary catheter and regular wound... (More)

Background Wound dehiscence is a known complication after anorectal malformations (ARMs) surgery. The aim was to evaluate if a standardized post-posterior sagittal anorectoplasty (PSARP) treatment program decreased wound dehiscence rates. Methods Wound dehiscence rates within 30 days post-PSARP were compared in a case-control single-center study between patients with a standardized post-PSARP treatment 2017-2023, and a cohort with a non-standardized management 2001-2016. The standardized post-PSARP program comprised a minimum of 3 days of: intravenous antibiotics imipenem+cilastatin (with optional subsequent oral amoxicillin+clavulanic acid+metronidazole), fasting after primary PSARP (no stoma), urinary catheter and regular wound cleansing. Results A total of 149 patients (61% males) with various ARM subtypes were included of which 51% were reconstructed with stomas. Overall, wound dehiscence developed in 8 of 59 patients (14%) in the standardized post-PSARP program group versus 28 of 90 patients (31%) in the control group (p=0.014). In primary PSARPs (no stoma, 59% males), wound dehiscence developed in 6 of 33 patients (18%) in the standardized post-PSARP program group versus 17 of 40 patients (43%) in the control group (p=0.026). Conclusion Wound dehiscence rates may be reduced using a standardized post-PSARP treatment program.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Colorectal Surgery, Congenital Abnormalities, Disabled Children, Patient Outcome Assessment, Pediatrics
in
World Journal of Pediatric Surgery
volume
8
issue
3
article number
e001003
publisher
BMJ Publishing Group
external identifiers
  • pmid:40519536
  • scopus:105007735916
ISSN
2516-5410
DOI
10.1136/wjps-2025-001003
language
English
LU publication?
yes
additional info
Publisher Copyright: © Author(s) (or their employer(s)) 2025.
id
b9e1daf0-bc56-469d-be39-00029e49b2c5
date added to LUP
2025-11-29 01:02:31
date last changed
2025-12-13 02:38:57
@article{b9e1daf0-bc56-469d-be39-00029e49b2c5,
  abstract     = {{<p>Background Wound dehiscence is a known complication after anorectal malformations (ARMs) surgery. The aim was to evaluate if a standardized post-posterior sagittal anorectoplasty (PSARP) treatment program decreased wound dehiscence rates. Methods Wound dehiscence rates within 30 days post-PSARP were compared in a case-control single-center study between patients with a standardized post-PSARP treatment 2017-2023, and a cohort with a non-standardized management 2001-2016. The standardized post-PSARP program comprised a minimum of 3 days of: intravenous antibiotics imipenem+cilastatin (with optional subsequent oral amoxicillin+clavulanic acid+metronidazole), fasting after primary PSARP (no stoma), urinary catheter and regular wound cleansing. Results A total of 149 patients (61% males) with various ARM subtypes were included of which 51% were reconstructed with stomas. Overall, wound dehiscence developed in 8 of 59 patients (14%) in the standardized post-PSARP program group versus 28 of 90 patients (31%) in the control group (p=0.014). In primary PSARPs (no stoma, 59% males), wound dehiscence developed in 6 of 33 patients (18%) in the standardized post-PSARP program group versus 17 of 40 patients (43%) in the control group (p=0.026). Conclusion Wound dehiscence rates may be reduced using a standardized post-PSARP treatment program.</p>}},
  author       = {{Tofft, Louise and Granéli, Christina and Hagelsteen, Kristine and Wester Fleur, Matilda and Stenström, Pernilla}},
  issn         = {{2516-5410}},
  keywords     = {{Colorectal Surgery; Congenital Abnormalities; Disabled Children; Patient Outcome Assessment; Pediatrics}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{3}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{World Journal of Pediatric Surgery}},
  title        = {{Wound dehiscence rates decreased in reconstructive surgery of anorectal malformations after introduction of a standardized postoperative treatment program}},
  url          = {{http://dx.doi.org/10.1136/wjps-2025-001003}},
  doi          = {{10.1136/wjps-2025-001003}},
  volume       = {{8}},
  year         = {{2025}},
}