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Características antigénicas de los virus aislados del líquido cefalorraquídeo de pacientes con neuropatía epidémica

Sarmiento Pérez, L ; Más Lago, P ; Avalos Redón, I ; Bello Corredor, M and Palomera Puentes, R (1998) In Revista cubana de medicina tropical 50 Suppl. p.4-231
Abstract

During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism... (More)

During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism through which these viruses take part in the etiopathogenesis of epidemic neuropathy in Cuba.

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author
alternative title
The antigenic characteristics of the viruses isolated from the cerebrospinal fluid of patients with epidemic neuropathy
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Antigens, Viral/analysis, Blotting, Western, Cerebrospinal Fluid/virology, Cuba/epidemiology, Disease Outbreaks, Enterovirus/immunology, Humans, Peripheral Nervous System Diseases/epidemiology
in
Revista cubana de medicina tropical
volume
50 Suppl
pages
4 pages
publisher
Editorial Ciencias Medicas
external identifiers
  • pmid:10349452
  • scopus:0032249289
ISSN
0375-0760
language
Spanish
LU publication?
no
id
b9e95735-ae5a-4845-9f2b-90d0633eff85
alternative location
http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601998000400002
date added to LUP
2019-07-08 15:17:46
date last changed
2020-01-13 02:12:33
@article{b9e95735-ae5a-4845-9f2b-90d0633eff85,
  abstract     = {<p>During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogenesis of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistence may be a mechanism through which these viruses take part in the etiopathogenesis of epidemic neuropathy in Cuba.</p>},
  author       = {Sarmiento Pérez, L and Más Lago, P and Avalos Redón, I and Bello Corredor, M and Palomera Puentes, R},
  issn         = {0375-0760},
  language     = {spa},
  pages        = {4--231},
  publisher    = {Editorial Ciencias Medicas},
  series       = {Revista cubana de medicina tropical},
  title        = {Características antigénicas de los virus aislados del líquido cefalorraquídeo de pacientes con neuropatía epidémica},
  url          = {http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601998000400002},
  volume       = {50 Suppl},
  year         = {1998},
}