Human prostate MRI at ultrahigh-performance gradient : A feasibility study
Zhu, Ante ; Tarasek, Matthew ; Hua, Yihe ; Fiveland, Eric ; Maier, Stephan E. ; Mazaheri, Yousef ; Fung, Maggie ; Westin, Carl Fredrik ; Yeo, Desmond T.B. and Szczepankiewicz, Filip LU
, et al.
(2024)
In Magnetic Resonance in Medicine
91(2).
p.640-648
- Abstract
Purpose: To demonstrate the technical feasibility and the value of ultrahigh-performance gradient in imaging the prostate in a 3T MRI system. Methods: In this local institutional review board–approved study, prostate MRI was performed on 4 healthy men. Each subject was scanned in a prototype 3T MRI system with a 42-cm inner-diameter gradient coil that achieves a maximum gradient amplitude of 200 mT/m and slew rate of 500 T/m/s. PI-RADS V2.1–compliant axial T2-weighted anatomical imaging and single-shot echo planar DWI at standard gradient of 70 mT/m and 150 T/m/s were obtained, followed by DWI at maximum performance (i.e., 200 mT/m and 500 T/m/s). In comparison to state-of-the-art clinical whole-body MRI systems, the high... (More)
Purpose: To demonstrate the technical feasibility and the value of ultrahigh-performance gradient in imaging the prostate in a 3T MRI system. Methods: In this local institutional review board–approved study, prostate MRI was performed on 4 healthy men. Each subject was scanned in a prototype 3T MRI system with a 42-cm inner-diameter gradient coil that achieves a maximum gradient amplitude of 200 mT/m and slew rate of 500 T/m/s. PI-RADS V2.1–compliant axial T2-weighted anatomical imaging and single-shot echo planar DWI at standard gradient of 70 mT/m and 150 T/m/s were obtained, followed by DWI at maximum performance (i.e., 200 mT/m and 500 T/m/s). In comparison to state-of-the-art clinical whole-body MRI systems, the high slew rate improved echo spacing from 1020 to 596 μs and, together with a high gradient amplitude for diffusion encoding, TE was reduced from 55 to 36 ms. Results: In all 4 subjects (waist circumference = 81–91 cm, age = 45–65 years), no peripheral nerve stimulation sensation was reported during DWI. Reduced image distortion in the posterior peripheral zone prostate gland and higher signal intensity, such as in the surrounding muscle of high-gradient DWI, were noted. Conclusion: Human prostate MRI at simultaneously high gradient amplitude of 200 mT/m and slew rate of 500 T/m/s is feasible, demonstrating that improved gradient performance can address image distortion and T2 decay–induced SNR issues for in vivo prostate imaging.
(Less)
- author
- Zhu, Ante
; Tarasek, Matthew
; Hua, Yihe
; Fiveland, Eric
; Maier, Stephan E.
; Mazaheri, Yousef
; Fung, Maggie
; Westin, Carl Fredrik
; Yeo, Desmond T.B.
and Szczepankiewicz, Filip
LU
, et al. (More)
- Zhu, Ante
; Tarasek, Matthew
; Hua, Yihe
; Fiveland, Eric
; Maier, Stephan E.
; Mazaheri, Yousef
; Fung, Maggie
; Westin, Carl Fredrik
; Yeo, Desmond T.B.
; Szczepankiewicz, Filip
LU
; Tempany, Clare
; Akin, Oguz
and Foo, Thomas K.F.
(Less)
- organization
- publishing date
- 2024-02
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diffusion MRI, echo time, image distortion, prostate, ultrahigh-performance gradient
- in
- Magnetic Resonance in Medicine
- volume
- 91
- issue
- 2
- pages
- 9 pages
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:37753628
- scopus:85172264348
- ISSN
- 0740-3194
- DOI
- 10.1002/mrm.29874
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2023 International Society for Magnetic Resonance in Medicine.
- id
- ba1449f1-2af8-407b-b630-ad692cbd68ff
- date added to LUP
- 2024-01-08 14:37:57
- date last changed
- 2024-04-23 10:13:38
@article{ba1449f1-2af8-407b-b630-ad692cbd68ff,
abstract = {{<p>Purpose: To demonstrate the technical feasibility and the value of ultrahigh-performance gradient in imaging the prostate in a 3T MRI system. Methods: In this local institutional review board–approved study, prostate MRI was performed on 4 healthy men. Each subject was scanned in a prototype 3T MRI system with a 42-cm inner-diameter gradient coil that achieves a maximum gradient amplitude of 200 mT/m and slew rate of 500 T/m/s. PI-RADS V2.1–compliant axial T<sub>2</sub>-weighted anatomical imaging and single-shot echo planar DWI at standard gradient of 70 mT/m and 150 T/m/s were obtained, followed by DWI at maximum performance (i.e., 200 mT/m and 500 T/m/s). In comparison to state-of-the-art clinical whole-body MRI systems, the high slew rate improved echo spacing from 1020 to 596 μs and, together with a high gradient amplitude for diffusion encoding, TE was reduced from 55 to 36 ms. Results: In all 4 subjects (waist circumference = 81–91 cm, age = 45–65 years), no peripheral nerve stimulation sensation was reported during DWI. Reduced image distortion in the posterior peripheral zone prostate gland and higher signal intensity, such as in the surrounding muscle of high-gradient DWI, were noted. Conclusion: Human prostate MRI at simultaneously high gradient amplitude of 200 mT/m and slew rate of 500 T/m/s is feasible, demonstrating that improved gradient performance can address image distortion and T<sub>2</sub> decay–induced SNR issues for in vivo prostate imaging.</p>}},
author = {{Zhu, Ante and Tarasek, Matthew and Hua, Yihe and Fiveland, Eric and Maier, Stephan E. and Mazaheri, Yousef and Fung, Maggie and Westin, Carl Fredrik and Yeo, Desmond T.B. and Szczepankiewicz, Filip and Tempany, Clare and Akin, Oguz and Foo, Thomas K.F.}},
issn = {{0740-3194}},
keywords = {{diffusion MRI; echo time; image distortion; prostate; ultrahigh-performance gradient}},
language = {{eng}},
number = {{2}},
pages = {{640--648}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Magnetic Resonance in Medicine}},
title = {{Human prostate MRI at ultrahigh-performance gradient : A feasibility study}},
url = {{http://dx.doi.org/10.1002/mrm.29874}},
doi = {{10.1002/mrm.29874}},
volume = {{91}},
year = {{2024}},
}