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The Benefits and Harms of Botulinum Toxin-A in the Treatment of Chronic Pelvic Pain Syndromes : A Systematic Review by the European Association of Urology Chronic Pelvic Pain Panel

Parsons, Brian A. ; Goonewardene, Sanchia ; Dabestani, Saeed LU ; Pacheco-Figueiredo, Luis ; Yuan, Yuhong ; Zumstein, Valentin ; Cottrell, Angela M. ; Borovicka, Jan ; Dinis-Oliveira, Paulo and Berghmans, Bary , et al. (2022) In European Urology Focus 8(1). p.320-338
Abstract

Chronic pelvic pain (CPP) is chronic or persistent pain perceived in structures related to the pelvis of men and women. Patients with CPP may have pain refractory to conventional management strategies. Botulinum toxin A (BTX-A) injection is a potential therapeutic option in patients with CPP. Beneficial effects of BTX-A on pain, quality of life, and functional symptoms were seen in patients with certain CPP subtypes, but the current evidence level is too weak to allow recommendations about the use of BTX-A for treating CPP. Therefore, larger-scale, multicentre, well-designed, and appropriately powered randomised controlled trials or prospective case-control studies with longer follow-up periods are needed.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bladder pain syndrome, Botulinum toxin A, Chronic anal fissure, Chronic pelvic pain syndrome, Gynaecological pain syndrome, Myofascial pelvic pain, Prostate pain syndrome
in
European Urology Focus
volume
8
issue
1
pages
320 - 338
publisher
Elsevier
external identifiers
  • scopus:85100174109
  • pmid:33526405
ISSN
2405-4569
DOI
10.1016/j.euf.2021.01.005
language
English
LU publication?
yes
id
ba3500c8-a6d6-4a92-8301-4a44bb44184d
date added to LUP
2021-02-15 10:38:22
date last changed
2024-04-18 01:57:09
@article{ba3500c8-a6d6-4a92-8301-4a44bb44184d,
  abstract     = {{<p>Chronic pelvic pain (CPP) is chronic or persistent pain perceived in structures related to the pelvis of men and women. Patients with CPP may have pain refractory to conventional management strategies. Botulinum toxin A (BTX-A) injection is a potential therapeutic option in patients with CPP. Beneficial effects of BTX-A on pain, quality of life, and functional symptoms were seen in patients with certain CPP subtypes, but the current evidence level is too weak to allow recommendations about the use of BTX-A for treating CPP. Therefore, larger-scale, multicentre, well-designed, and appropriately powered randomised controlled trials or prospective case-control studies with longer follow-up periods are needed.</p>}},
  author       = {{Parsons, Brian A. and Goonewardene, Sanchia and Dabestani, Saeed and Pacheco-Figueiredo, Luis and Yuan, Yuhong and Zumstein, Valentin and Cottrell, Angela M. and Borovicka, Jan and Dinis-Oliveira, Paulo and Berghmans, Bary and Elneil, Sohier and Hughes, John and Messelink, Bert E.J. and de C Williams, Amanda C. and Baranowski, Andrew P. and Engeler, Daniel S.}},
  issn         = {{2405-4569}},
  keywords     = {{Bladder pain syndrome; Botulinum toxin A; Chronic anal fissure; Chronic pelvic pain syndrome; Gynaecological pain syndrome; Myofascial pelvic pain; Prostate pain syndrome}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{320--338}},
  publisher    = {{Elsevier}},
  series       = {{European Urology Focus}},
  title        = {{The Benefits and Harms of Botulinum Toxin-A in the Treatment of Chronic Pelvic Pain Syndromes : A Systematic Review by the European Association of Urology Chronic Pelvic Pain Panel}},
  url          = {{http://dx.doi.org/10.1016/j.euf.2021.01.005}},
  doi          = {{10.1016/j.euf.2021.01.005}},
  volume       = {{8}},
  year         = {{2022}},
}