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Monitoring time-to-detection of recurrent atrial fibrillation in patients with transient new-onset atrial fibrillation detected initially during hospitalization for noncardiac surgery or medical illness

McIntyre, William F. ; Johnson, Linda S. LU ; Benz, Alexander P. ; Vadakken, Maria E. ; Latendresse, Nicole R. ; Ramasundarahettige, Chinthanie ; Kirabo, Faith ; Wong, Jorge A. ; Roberts, Jason D. and Healey, Jeff S. (2026) In European Journal of Internal Medicine 144.
Abstract

Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of participants with transient new-onset AF while hospitalized for noncardiac surgery or medical illness, who wore one or two 14-day ECG monitors. We calculated the proportion of patients that would be diagnosed with recurrent AF with different durations of ECG monitoring and the median time-to-detection of recurrent AF lasting ≥30 s. Results A total... (More)

Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of participants with transient new-onset AF while hospitalized for noncardiac surgery or medical illness, who wore one or two 14-day ECG monitors. We calculated the proportion of patients that would be diagnosed with recurrent AF with different durations of ECG monitoring and the median time-to-detection of recurrent AF lasting ≥30 s. Results A total of 139 participants (41.0 % female, median CHA2DS2-VASc 3) wore an ECG monitor a median of 1.5 months following hospital discharge; 83 (59.7 %) wore a second monitor at median of 5.8 months after the first monitor. Recurrent AF was detected in 5.0 % of participants by 1 day, 5.8 % by 2 days, 6.5 % by 3 days, 12.2 % by 7 days, 21.6 % by 14 days and in 28.8 % by the end of the second 14-day monitor. Median monitoring time to recurrent AF was 5.3 (IQR 1.4–9.7) days. Conclusions In patients with transient new-onset AF during hospitalization for another reason, the rate of detection of recurrent AF increased with longer monitoring durations. Approximately 80 % of diagnoses were made after 2 days of monitoring; the likelihood of capturing recurrent AF was 4 times higher with 14 days of monitoring compared to 2 days.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Atrial fibrillation, Holter, Provoked, reversible, Secondary, Triggered
in
European Journal of Internal Medicine
volume
144
article number
106515
publisher
Elsevier
external identifiers
  • pmid:41073249
  • scopus:105026211611
ISSN
0953-6205
DOI
10.1016/j.ejim.2025.106515
language
English
LU publication?
yes
id
ba3d5373-a6a2-448f-8dfd-0a9bedade0ea
date added to LUP
2026-02-23 10:07:20
date last changed
2026-02-23 10:07:53
@article{ba3d5373-a6a2-448f-8dfd-0a9bedade0ea,
  abstract     = {{<p>Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of participants with transient new-onset AF while hospitalized for noncardiac surgery or medical illness, who wore one or two 14-day ECG monitors. We calculated the proportion of patients that would be diagnosed with recurrent AF with different durations of ECG monitoring and the median time-to-detection of recurrent AF lasting ≥30 s. Results A total of 139 participants (41.0 % female, median CHA<sub>2</sub>DS<sub>2</sub>-VASc 3) wore an ECG monitor a median of 1.5 months following hospital discharge; 83 (59.7 %) wore a second monitor at median of 5.8 months after the first monitor. Recurrent AF was detected in 5.0 % of participants by 1 day, 5.8 % by 2 days, 6.5 % by 3 days, 12.2 % by 7 days, 21.6 % by 14 days and in 28.8 % by the end of the second 14-day monitor. Median monitoring time to recurrent AF was 5.3 (IQR 1.4–9.7) days. Conclusions In patients with transient new-onset AF during hospitalization for another reason, the rate of detection of recurrent AF increased with longer monitoring durations. Approximately 80 % of diagnoses were made after 2 days of monitoring; the likelihood of capturing recurrent AF was 4 times higher with 14 days of monitoring compared to 2 days.</p>}},
  author       = {{McIntyre, William F. and Johnson, Linda S. and Benz, Alexander P. and Vadakken, Maria E. and Latendresse, Nicole R. and Ramasundarahettige, Chinthanie and Kirabo, Faith and Wong, Jorge A. and Roberts, Jason D. and Healey, Jeff S.}},
  issn         = {{0953-6205}},
  keywords     = {{Atrial fibrillation; Holter; Provoked; reversible; Secondary; Triggered}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Internal Medicine}},
  title        = {{Monitoring time-to-detection of recurrent atrial fibrillation in patients with transient new-onset atrial fibrillation detected initially during hospitalization for noncardiac surgery or medical illness}},
  url          = {{http://dx.doi.org/10.1016/j.ejim.2025.106515}},
  doi          = {{10.1016/j.ejim.2025.106515}},
  volume       = {{144}},
  year         = {{2026}},
}