KinMutBase, a database of human disease-causing protein kinase mutations
Stenberg, KAE ; Riikonen, PT and Vihinen, Mauno LU
(2000)
In Nucleic Acids Research
28(1).
p.369-371
- Abstract
- KinMutBase (http://www.uta.fi/imt/bioinfo/KinMutBase/) is a registry of mutations in human protein kinases related to-disorders. Kinases are essential cellular signaling molecules, in which mutations can lead to diseases, including immunodeficiencies, cancers and endocrine disorders, The first release of KinMutBase contained information for protein tyrosine kinases. The current release includes also serine/threonine protein kinases, as well as an update of the tyrosine kinases, There are 251 entries altogether, representing 337 families and 621 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics... (More)
- KinMutBase (http://www.uta.fi/imt/bioinfo/KinMutBase/) is a registry of mutations in human protein kinases related to-disorders. Kinases are essential cellular signaling molecules, in which mutations can lead to diseases, including immunodeficiencies, cancers and endocrine disorders, The first release of KinMutBase contained information for protein tyrosine kinases. The current release includes also serine/threonine protein kinases, as well as an update of the tyrosine kinases, There are 251 entries altogether, representing 337 families and 621 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics land display, clickable sequences with mutations and changes to restriction enzyme patterns. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3852294
- author
- Stenberg, KAE
; Riikonen, PT
and Vihinen, Mauno
LU
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nucleic Acids Research
- volume
- 28
- issue
- 1
- pages
- 369 - 371
- publisher
- Oxford University Press
- external identifiers
-
- wos:000084896300110
- scopus:0033970710
- ISSN
- 1362-4962
- DOI
- 10.1093/nar/28.1.369
- language
- English
- LU publication?
- no
- id
- baf414bb-30a2-4dbd-a71c-aa37584c7435 (old id 3852294)
- date added to LUP
- 2016-04-01 12:33:38
- date last changed
- 2022-01-27 06:44:09
@article{baf414bb-30a2-4dbd-a71c-aa37584c7435,
abstract = {{KinMutBase (http://www.uta.fi/imt/bioinfo/KinMutBase/) is a registry of mutations in human protein kinases related to-disorders. Kinases are essential cellular signaling molecules, in which mutations can lead to diseases, including immunodeficiencies, cancers and endocrine disorders, The first release of KinMutBase contained information for protein tyrosine kinases. The current release includes also serine/threonine protein kinases, as well as an update of the tyrosine kinases, There are 251 entries altogether, representing 337 families and 621 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics land display, clickable sequences with mutations and changes to restriction enzyme patterns.}},
author = {{Stenberg, KAE and Riikonen, PT and Vihinen, Mauno}},
issn = {{1362-4962}},
language = {{eng}},
number = {{1}},
pages = {{369--371}},
publisher = {{Oxford University Press}},
series = {{Nucleic Acids Research}},
title = {{KinMutBase, a database of human disease-causing protein kinase mutations}},
url = {{http://dx.doi.org/10.1093/nar/28.1.369}},
doi = {{10.1093/nar/28.1.369}},
volume = {{28}},
year = {{2000}},
}