Total body hyperthermia induced by a computerized microwave technique : studies in normal rats and in rats with liver tumors.
Hugander, A. ; Carlsson, G. ; Hafström, L. ; Jönsson, P. E. LU ; Hultberg, B. LU ; Bolmsjö, M. and Persson, B. LU
(1983)
In Anticancer research
3(3).
p.161-165
- Abstract
A computerized system for inducing total body hyperthermia by microwave irradiation was tested in rats. The tolerance to hyperthermia at different temperatures and fractions was studied as well as its effect on the growth of transplanted adenocarcinomas in the liver. Survival results indicated that 41.5 degrees C was maximum tolerated temperature both after single and repeated one hour exposures. Besides the high mortality with a greater temperature (42 degrees C) there was a significant rise in S-aspartate-amino-transferase (S-ASAT) and S-beta-hexosaminidase (beta-nagas) indicating damage of normal cells. No significant reduction of tumor volume could be registered after treatment with total body hyperthermia (41.5 degrees C) for one... (More)
A computerized system for inducing total body hyperthermia by microwave irradiation was tested in rats. The tolerance to hyperthermia at different temperatures and fractions was studied as well as its effect on the growth of transplanted adenocarcinomas in the liver. Survival results indicated that 41.5 degrees C was maximum tolerated temperature both after single and repeated one hour exposures. Besides the high mortality with a greater temperature (42 degrees C) there was a significant rise in S-aspartate-amino-transferase (S-ASAT) and S-beta-hexosaminidase (beta-nagas) indicating damage of normal cells. No significant reduction of tumor volume could be registered after treatment with total body hyperthermia (41.5 degrees C) for one hour three times during a 24 hour period.
(Less)
- author
- Hugander, A.
; Carlsson, G.
; Hafström, L.
; Jönsson, P. E.
LU
; Hultberg, B.
LU
; Bolmsjö, M.
and Persson, B.
LU
- organization
- publishing date
- 1983-05-01
- type
- Contribution to journal
- publication status
- published
- in
- Anticancer research
- volume
- 3
- issue
- 3
- pages
- 5 pages
- publisher
- International Institute of Cancer Research
- external identifiers
-
- scopus:0020755418
- pmid:6870197
- ISSN
- 0250-7005
- language
- English
- LU publication?
- yes
- id
- bb0c6bb8-7b13-4046-938f-6cf41d730d43
- date added to LUP
- 2020-05-07 21:27:44
- date last changed
- 2024-01-02 10:54:52
@article{bb0c6bb8-7b13-4046-938f-6cf41d730d43,
abstract = {{<p>A computerized system for inducing total body hyperthermia by microwave irradiation was tested in rats. The tolerance to hyperthermia at different temperatures and fractions was studied as well as its effect on the growth of transplanted adenocarcinomas in the liver. Survival results indicated that 41.5 degrees C was maximum tolerated temperature both after single and repeated one hour exposures. Besides the high mortality with a greater temperature (42 degrees C) there was a significant rise in S-aspartate-amino-transferase (S-ASAT) and S-beta-hexosaminidase (beta-nagas) indicating damage of normal cells. No significant reduction of tumor volume could be registered after treatment with total body hyperthermia (41.5 degrees C) for one hour three times during a 24 hour period.</p>}},
author = {{Hugander, A. and Carlsson, G. and Hafström, L. and Jönsson, P. E. and Hultberg, B. and Bolmsjö, M. and Persson, B.}},
issn = {{0250-7005}},
language = {{eng}},
month = {{05}},
number = {{3}},
pages = {{161--165}},
publisher = {{International Institute of Cancer Research}},
series = {{Anticancer research}},
title = {{Total body hyperthermia induced by a computerized microwave technique : studies in normal rats and in rats with liver tumors.}},
volume = {{3}},
year = {{1983}},
}