Do Probiotics Cause a Shift in the Microbiota of Dental Implants-A Systematic Review and Meta-Analysis
(2022) In Frontiers in cellular and infection microbiology 12. p.1-10- Abstract
OBJECTIVE: The primary aim of this current systematic review and meta-analysis was to evaluate the potential microbiological effect of probiotics on the implant microbiota. The secondary aim was to evaluate if probiotics have any effect as an adjunct to non-surgical peri-implant treatment in reducing peri-implant mucositis and peri-implantitis clinical parameters-bleeding on probing, modified Gingival Index, and pocket depth.
METHODS: The research focus questions were constructed in accordance with the Participants, Intervention, Comparison, and Outcomes (PICO) criteria, and a PROSPERO protocol was registered. A comprehensive systematic search in MEDLINE via the PubMed, Scopus, and Web of Science Core Collection databases was... (More)
OBJECTIVE: The primary aim of this current systematic review and meta-analysis was to evaluate the potential microbiological effect of probiotics on the implant microbiota. The secondary aim was to evaluate if probiotics have any effect as an adjunct to non-surgical peri-implant treatment in reducing peri-implant mucositis and peri-implantitis clinical parameters-bleeding on probing, modified Gingival Index, and pocket depth.
METHODS: The research focus questions were constructed in accordance with the Participants, Intervention, Comparison, and Outcomes (PICO) criteria, and a PROSPERO protocol was registered. A comprehensive systematic search in MEDLINE via the PubMed, Scopus, and Web of Science Core Collection databases was conducted. Two independent reviewers screened the reports based on the PICO criteria-inclusion and exclusion criteria.
RESULTS: In total, 467 records were identified, and ultimately, 7 papers were included: 3 papers in the qualitative synthesis of microbiological effect and 4 in the meta-analysis synthesis on pocket depth. The data synthesis showed that probiotics had no detectable effect on the implant microflora, and in the following data synthesis, no clinical peri-implantitis variable showed a significantly beneficial effect from probiotics in the test group compared to the control group.
CONCLUSION: Within the limitations of this review, the oral implant microflora is not affected by probiotics nor do probiotics add any effect to the conventional non-surgical treatment of peri-implant mucositis and peri-implantitis.
(Less)
- author
- Sayardoust, Shariel ; Johansson, Anders LU and Jönsson, Daniel LU
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Dental Implants/adverse effects, Humans, Microbiota, Peri-Implantitis/etiology, Probiotics/therapeutic use, Stomatitis/complications
- in
- Frontiers in cellular and infection microbiology
- volume
- 12
- article number
- 823985
- pages
- 1 - 10
- publisher
- Frontiers Media S. A.
- external identifiers
-
- scopus:85127516366
- pmid:35372118
- ISSN
- 2235-2988
- DOI
- 10.3389/fcimb.2022.823985
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2022 Sayardoust, Johansson and Jönsson.
- id
- bb4565a5-cb01-41e7-9ec7-1caac88f3b92
- date added to LUP
- 2024-07-04 10:33:15
- date last changed
- 2025-05-10 12:37:02
@article{bb4565a5-cb01-41e7-9ec7-1caac88f3b92,
abstract = {{<p>OBJECTIVE: The primary aim of this current systematic review and meta-analysis was to evaluate the potential microbiological effect of probiotics on the implant microbiota. The secondary aim was to evaluate if probiotics have any effect as an adjunct to non-surgical peri-implant treatment in reducing peri-implant mucositis and peri-implantitis clinical parameters-bleeding on probing, modified Gingival Index, and pocket depth.</p><p>METHODS: The research focus questions were constructed in accordance with the Participants, Intervention, Comparison, and Outcomes (PICO) criteria, and a PROSPERO protocol was registered. A comprehensive systematic search in MEDLINE via the PubMed, Scopus, and Web of Science Core Collection databases was conducted. Two independent reviewers screened the reports based on the PICO criteria-inclusion and exclusion criteria.</p><p>RESULTS: In total, 467 records were identified, and ultimately, 7 papers were included: 3 papers in the qualitative synthesis of microbiological effect and 4 in the meta-analysis synthesis on pocket depth. The data synthesis showed that probiotics had no detectable effect on the implant microflora, and in the following data synthesis, no clinical peri-implantitis variable showed a significantly beneficial effect from probiotics in the test group compared to the control group.</p><p>CONCLUSION: Within the limitations of this review, the oral implant microflora is not affected by probiotics nor do probiotics add any effect to the conventional non-surgical treatment of peri-implant mucositis and peri-implantitis.</p>}},
author = {{Sayardoust, Shariel and Johansson, Anders and Jönsson, Daniel}},
issn = {{2235-2988}},
keywords = {{Dental Implants/adverse effects; Humans; Microbiota; Peri-Implantitis/etiology; Probiotics/therapeutic use; Stomatitis/complications}},
language = {{eng}},
pages = {{1--10}},
publisher = {{Frontiers Media S. A.}},
series = {{Frontiers in cellular and infection microbiology}},
title = {{Do Probiotics Cause a Shift in the Microbiota of Dental Implants-A Systematic Review and Meta-Analysis}},
url = {{http://dx.doi.org/10.3389/fcimb.2022.823985}},
doi = {{10.3389/fcimb.2022.823985}},
volume = {{12}},
year = {{2022}},
}