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A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens

Hellberg, Åsa LU ; Pesjak, Emma ; Karlsson, Jessica and Storry, Jill R. LU (2016) In Transfusion 56(9). p.2391-2392
Abstract

We report a novel RHCE*02 allele in a Swedish blood donor that is characterized by the change c.460A>G (Arg154Gly). The blood donor's red blood cells showed variable reactivity with different monoclonal anti-C and anti-e and antigen strength was markedly weakened. We believe that these changes represent both a quantitative and qualitative alteration of the antigens encoded by this allele.

Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Transfusion
volume
56
issue
9
pages
2 pages
publisher
Wiley-Blackwell
external identifiers
  • pmid:27282785
  • wos:000385837900035
  • scopus:84987621248
ISSN
0041-1132
DOI
10.1111/trf.13679
language
English
LU publication?
yes
id
bc1a67f2-713e-4b9d-a1ed-3373330ef67a
date added to LUP
2016-10-06 09:09:19
date last changed
2025-01-12 12:46:07
@article{bc1a67f2-713e-4b9d-a1ed-3373330ef67a,
  abstract     = {{<p>We report a novel RHCE*02 allele in a Swedish blood donor that is characterized by the change c.460A&gt;G (Arg154Gly). The blood donor's red blood cells showed variable reactivity with different monoclonal anti-C and anti-e and antigen strength was markedly weakened. We believe that these changes represent both a quantitative and qualitative alteration of the antigens encoded by this allele.</p>}},
  author       = {{Hellberg, Åsa and Pesjak, Emma and Karlsson, Jessica and Storry, Jill R.}},
  issn         = {{0041-1132}},
  language     = {{eng}},
  month        = {{09}},
  number       = {{9}},
  pages        = {{2391--2392}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Transfusion}},
  title        = {{A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens}},
  url          = {{https://lup.lub.lu.se/search/files/21272768/13581132.pdf}},
  doi          = {{10.1111/trf.13679}},
  volume       = {{56}},
  year         = {{2016}},
}