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Subjectively Reported Effects Experienced in an Actively Shielded 7T MRI : A Large-Scale Study

Hansson, Boel LU ; Markenroth Bloch, Karin LU ; Owman, Titti LU ; Nilsson, Markus LU ; Lätt, Jimmy LU ; Olsrud, Johan LU and Björkman-Burtscher, Isabella M. LU (2020) In Journal of Magnetic Resonance Imaging
Abstract

Background: Ultrahigh-field (UHF) MRI advances towards clinical use. Patient compliance is generally high, but few large-scale studies have investigated the effects experienced in 7T MRI systems, especially considering peripheral nerve stimulation (PNS) and caregiving. Purpose: To evaluate the quantity, the intensity, and subjective experiences from short-term effects, focusing on the levels of comfort and compliance of subjects. Study Type: Prospective. Population: In all, 954 consecutive MRIs in 801 subjects for 3 years. Field Strength: 7T. Assessment: After the 7T examination, a questionnaire was used to collect data. Statistical Tests: Descriptive statistics, Spearman's rank correlation, Mann–Whitney U-test, and t-test. Results: The... (More)

Background: Ultrahigh-field (UHF) MRI advances towards clinical use. Patient compliance is generally high, but few large-scale studies have investigated the effects experienced in 7T MRI systems, especially considering peripheral nerve stimulation (PNS) and caregiving. Purpose: To evaluate the quantity, the intensity, and subjective experiences from short-term effects, focusing on the levels of comfort and compliance of subjects. Study Type: Prospective. Population: In all, 954 consecutive MRIs in 801 subjects for 3 years. Field Strength: 7T. Assessment: After the 7T examination, a questionnaire was used to collect data. Statistical Tests: Descriptive statistics, Spearman's rank correlation, Mann–Whitney U-test, and t-test. Results: The majority (63%) of subjects agreed that the MRI experience was comfortable and 93% would be willing to undergo future 7T MRI as a patient (5% undecided) and 82% for research purposes (12% undecided). The most common short-term effects experienced were dizziness (81%), inconsistent movement (68%), PNS (63%), headache (40%), nausea (32%), metallic taste (12%), and light flashes (8%). Of the subjects who reported having PNS (n = 603), 44% experienced PNS as “not uncomfortable at all,” 45% as “little or very little uncomfortable,” and 11% as “moderate to very much uncomfortable.” Scanner room temperature was experienced more comfortable before (78%) than during (58%) examinations, and the noise level was acceptable by 90% of subjects. Anxiety before the examination was reported by 43%. Patients differed from healthy volunteers regarding an experience of headache, metallic taste, dizziness, or anxiety. Room for improvement was pointed out after 117 examinations concerning given information (n = 73), communication and sound system (n = 35), or nursing care (n = 15). Data Conclusion: Subjectively reported effects occur in actively shielded 7T MRI and include physiological responses and individual psychological issues. Although leaving room for improvement, few subjects experienced these effects being so uncomfortable that they would lead to aversion to future UHF examinations. Level of Evidence: 1. Technical Efficacy: Stage 5.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
anxiety, dizziness, patient compliance, peripheral nerve stimulation, safety, ultrahigh field
in
Journal of Magnetic Resonance Imaging
publisher
John Wiley and Sons Inc.
external identifiers
  • scopus:85082052592
  • pmid:32196818
ISSN
1053-1807
DOI
10.1002/jmri.27139
language
English
LU publication?
yes
id
bd2544e6-0d0d-492b-8751-5301d15f5681
date added to LUP
2020-04-08 09:51:54
date last changed
2020-04-09 01:57:38
@article{bd2544e6-0d0d-492b-8751-5301d15f5681,
  abstract     = {<p>Background: Ultrahigh-field (UHF) MRI advances towards clinical use. Patient compliance is generally high, but few large-scale studies have investigated the effects experienced in 7T MRI systems, especially considering peripheral nerve stimulation (PNS) and caregiving. Purpose: To evaluate the quantity, the intensity, and subjective experiences from short-term effects, focusing on the levels of comfort and compliance of subjects. Study Type: Prospective. Population: In all, 954 consecutive MRIs in 801 subjects for 3 years. Field Strength: 7T. Assessment: After the 7T examination, a questionnaire was used to collect data. Statistical Tests: Descriptive statistics, Spearman's rank correlation, Mann–Whitney U-test, and t-test. Results: The majority (63%) of subjects agreed that the MRI experience was comfortable and 93% would be willing to undergo future 7T MRI as a patient (5% undecided) and 82% for research purposes (12% undecided). The most common short-term effects experienced were dizziness (81%), inconsistent movement (68%), PNS (63%), headache (40%), nausea (32%), metallic taste (12%), and light flashes (8%). Of the subjects who reported having PNS (n = 603), 44% experienced PNS as “not uncomfortable at all,” 45% as “little or very little uncomfortable,” and 11% as “moderate to very much uncomfortable.” Scanner room temperature was experienced more comfortable before (78%) than during (58%) examinations, and the noise level was acceptable by 90% of subjects. Anxiety before the examination was reported by 43%. Patients differed from healthy volunteers regarding an experience of headache, metallic taste, dizziness, or anxiety. Room for improvement was pointed out after 117 examinations concerning given information (n = 73), communication and sound system (n = 35), or nursing care (n = 15). Data Conclusion: Subjectively reported effects occur in actively shielded 7T MRI and include physiological responses and individual psychological issues. Although leaving room for improvement, few subjects experienced these effects being so uncomfortable that they would lead to aversion to future UHF examinations. Level of Evidence: 1. Technical Efficacy: Stage 5.</p>},
  author       = {Hansson, Boel and Markenroth Bloch, Karin and Owman, Titti and Nilsson, Markus and Lätt, Jimmy and Olsrud, Johan and Björkman-Burtscher, Isabella M.},
  issn         = {1053-1807},
  language     = {eng},
  month        = {03},
  publisher    = {John Wiley and Sons Inc.},
  series       = {Journal of Magnetic Resonance Imaging},
  title        = {Subjectively Reported Effects Experienced in an Actively Shielded 7T MRI : A Large-Scale Study},
  url          = {http://dx.doi.org/10.1002/jmri.27139},
  doi          = {10.1002/jmri.27139},
  year         = {2020},
}