Airway epithelial repair: breathtakingly quick and multipotentially pathogenic
(1997) In Thorax 52(11). p.1010-1012- Abstract
- Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1112489
- author
- Erjefält, Jonas LU and Persson, Carl LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- asthma pathology, mucosal barrier, epithelial repair
- in
- Thorax
- volume
- 52
- issue
- 11
- pages
- 1010 - 1012
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:9487352
- scopus:0030778321
- ISSN
- 1468-3296
- language
- English
- LU publication?
- yes
- id
- bd2df619-1f95-4b9f-a7e0-9057dd398d40 (old id 1112489)
- alternative location
- http://thorax.bmj.com/cgi/reprint/52/11/1010
- date added to LUP
- 2016-04-01 16:26:37
- date last changed
- 2022-01-28 19:45:00
@article{bd2df619-1f95-4b9f-a7e0-9057dd398d40, abstract = {{Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.}}, author = {{Erjefält, Jonas and Persson, Carl}}, issn = {{1468-3296}}, keywords = {{asthma pathology; mucosal barrier; epithelial repair}}, language = {{eng}}, number = {{11}}, pages = {{1010--1012}}, publisher = {{BMJ Publishing Group}}, series = {{Thorax}}, title = {{Airway epithelial repair: breathtakingly quick and multipotentially pathogenic}}, url = {{http://thorax.bmj.com/cgi/reprint/52/11/1010}}, volume = {{52}}, year = {{1997}}, }