Cost-effectiveness of prophylaxis against on-demand treatment in boys with severe hemophilia A in Iran.
Ahmad Kia Daliri, Aliasghar LU
; Haghparast, Hassan
and Mamikhani, Jahanara
(2009)
In International Journal of Technology Assessment in Health Care
25(4).
p.584-587
- Abstract
- Objective: The aim of this study was to assess the incremental cost-effectiveness of on-demand versus prophylactic hemophilia therapy in Iran from a third-party payers’ perspective.
Methods: A retrospective chart review of twenty-five type A hemophiliacs who were treated in three hemophilia treatment centers was conducted. The patients were boys 0–9 years old receiving one of two treatments: (i) prophylaxis with concentrate at clinic; (ii) concentrate at clinic as on-demand. Fourteen boys received on-demand infusions for bleeding events, and eleven boys received infusions prophylaxis. Data were extracted from documents in the hemophilia treatment centers during a period of approximately 6 months.
Results: The patients... (More) - Objective: The aim of this study was to assess the incremental cost-effectiveness of on-demand versus prophylactic hemophilia therapy in Iran from a third-party payers’ perspective.
Methods: A retrospective chart review of twenty-five type A hemophiliacs who were treated in three hemophilia treatment centers was conducted. The patients were boys 0–9 years old receiving one of two treatments: (i) prophylaxis with concentrate at clinic; (ii) concentrate at clinic as on-demand. Fourteen boys received on-demand infusions for bleeding events, and eleven boys received infusions prophylaxis. Data were extracted from documents in the hemophilia treatment centers during a period of approximately 6 months.
Results: The patients receiving prophylactic treatment had fewer bleeding events each month (mean, 0.26 versus 2.74) but used more concentrate (225.31 versus 87.20 units/kg per month). Average monthly cost per patient in the prophylaxis group was approximately 1.9 times higher than in the on-demand group. Compared with on-demand infusion, prophylaxis costs 3,201,656 Rials (€213.45) per bleeding event prevented.
Conclusion: Prophylactic care markedly reduces the number of bleeding episodes, but at considerable cost. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1982703
- author
- Ahmad Kia Daliri, Aliasghar
LU
; Haghparast, Hassan
and Mamikhani, Jahanara
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- in
- International Journal of Technology Assessment in Health Care
- volume
- 25
- issue
- 4
- pages
- 584 - 587
- publisher
- Cambridge University Press
- external identifiers
-
- scopus:74049131031
- ISSN
- 1471-6348
- language
- English
- LU publication?
- no
- id
- bd7069fd-4737-4d5c-aece-f3aaec30be3a (old id 1982703)
- alternative location
- http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=6375896
- date added to LUP
- 2016-04-04 10:20:49
- date last changed
- 2025-12-16 10:37:08
@article{bd7069fd-4737-4d5c-aece-f3aaec30be3a,
abstract = {{Objective: The aim of this study was to assess the incremental cost-effectiveness of on-demand versus prophylactic hemophilia therapy in Iran from a third-party payers’ perspective.<br/><br/>Methods: A retrospective chart review of twenty-five type A hemophiliacs who were treated in three hemophilia treatment centers was conducted. The patients were boys 0–9 years old receiving one of two treatments: (i) prophylaxis with concentrate at clinic; (ii) concentrate at clinic as on-demand. Fourteen boys received on-demand infusions for bleeding events, and eleven boys received infusions prophylaxis. Data were extracted from documents in the hemophilia treatment centers during a period of approximately 6 months.<br/><br/>Results: The patients receiving prophylactic treatment had fewer bleeding events each month (mean, 0.26 versus 2.74) but used more concentrate (225.31 versus 87.20 units/kg per month). Average monthly cost per patient in the prophylaxis group was approximately 1.9 times higher than in the on-demand group. Compared with on-demand infusion, prophylaxis costs 3,201,656 Rials (€213.45) per bleeding event prevented.<br/><br/>Conclusion: Prophylactic care markedly reduces the number of bleeding episodes, but at considerable cost.}},
author = {{Ahmad Kia Daliri, Aliasghar and Haghparast, Hassan and Mamikhani, Jahanara}},
issn = {{1471-6348}},
language = {{eng}},
number = {{4}},
pages = {{584--587}},
publisher = {{Cambridge University Press}},
series = {{International Journal of Technology Assessment in Health Care}},
title = {{Cost-effectiveness of prophylaxis against on-demand treatment in boys with severe hemophilia A in Iran.}},
url = {{http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=6375896}},
volume = {{25}},
year = {{2009}},
}