Mitotic Count and Estimation of the Risk of GIST Recurrence in Patients Treated with Preoperative Imatinib
(2019) In Clinical Oncology and Research 2(5). p.1-2- Abstract
- Preoperative imatinib is used frequently in the treatment of large localized GISTs to shrink the tumor prior to surgery. This approach may lead to challenges in the estimation of the risk of recurrence and the need of adjuvant imatinib, because the diagnosis is usually made from a needle biopsy with scant tissue for the assessment of GIST mitotic activity, a key prognostic factor. We propose a mitosis count multiplication method as a proxy for estimating the tumor mitotic count in select cases.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/bdcb3460-4b29-45d0-8326-55daaecd770c
- author
- Eriksson, Mikael LU and Joensuu, Heikki
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Oncology and Research
- volume
- 2
- issue
- 5
- pages
- 1 - 2
- publisher
- Science Repository
- ISSN
- 2613-4942
- language
- English
- LU publication?
- yes
- id
- bdcb3460-4b29-45d0-8326-55daaecd770c
- alternative location
- https://www.sciencerepository.org/mitotic-count-and-estimation-of-the-risk-of-gist-recurrence_COR-2019-5-115
- date added to LUP
- 2020-03-02 16:01:28
- date last changed
- 2020-03-02 16:01:28
@misc{bdcb3460-4b29-45d0-8326-55daaecd770c, abstract = {{Preoperative imatinib is used frequently in the treatment of large localized GISTs to shrink the tumor prior to surgery. This approach may lead to challenges in the estimation of the risk of recurrence and the need of adjuvant imatinib, because the diagnosis is usually made from a needle biopsy with scant tissue for the assessment of GIST mitotic activity, a key prognostic factor. We propose a mitosis count multiplication method as a proxy for estimating the tumor mitotic count in select cases.}}, author = {{Eriksson, Mikael and Joensuu, Heikki}}, issn = {{2613-4942}}, language = {{eng}}, number = {{5}}, pages = {{1--2}}, publisher = {{Science Repository}}, series = {{Clinical Oncology and Research}}, title = {{Mitotic Count and Estimation of the Risk of GIST Recurrence in Patients Treated with Preoperative Imatinib}}, url = {{https://www.sciencerepository.org/mitotic-count-and-estimation-of-the-risk-of-gist-recurrence_COR-2019-5-115}}, volume = {{2}}, year = {{2019}}, }