Health-related quality of life and long-term symptoms among patients with non-severe covid-19–a prospective cohort study
(2023) In Infectious Diseases 55(4). p.272-281- Abstract
Background: The vast majority of covid-19 patients experience non-severe disease. Nonetheless, long-term symptoms may be common and the impact on quality of life is uncertain. This study aims to examine these aspects in a prospective, longitudinal cohort. Methods: Non-hospitalised patients with PCR-confirmed covid-19 were prospectively invited to self-report assessments of background data, symptoms and recovery, illness perception (BIPQ) and health-related quality of life (HR-Qol) measured by EQ5D-VAS. Results: 154 patients were included (mean age 46 years, 69% female). The majority of participants (65%) had symptoms for 1–4 weeks and 12% more than 6 months. The most common symptoms were initially malaise, fatigue, headache, fever and... (More)
Background: The vast majority of covid-19 patients experience non-severe disease. Nonetheless, long-term symptoms may be common and the impact on quality of life is uncertain. This study aims to examine these aspects in a prospective, longitudinal cohort. Methods: Non-hospitalised patients with PCR-confirmed covid-19 were prospectively invited to self-report assessments of background data, symptoms and recovery, illness perception (BIPQ) and health-related quality of life (HR-Qol) measured by EQ5D-VAS. Results: 154 patients were included (mean age 46 years, 69% female). The majority of participants (65%) had symptoms for 1–4 weeks and 12% more than 6 months. The most common symptoms were initially malaise, fatigue, headache, fever and cough and the most common long-term symptoms were impaired physical condition, fatigue, anosmia and headache. The BIPQ index had a negative correlation with the EQ5D-VAS score after the infection, but not with long-term symptoms. Mean differences in the EQ5D-VAS score were significantly lower after the infection and patients with long-term symptoms had a more pronounced negative effect in EQ5D-VAS scores. Conclusion: We found that most patients with non-severe covid-19 reported symptoms for 1–4 weeks and approximately 10% developed long-term symptoms. Non-severe covid-19 seems to have a negative influence on HR-Qol, especially in patients with long-term symptoms and with a greater burden from the disease. None of the initial symptoms could predict the presence of long-term symptoms.
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- author
- Löfström, Emma LU ; Kunkel, Stefan ; Kötz, Arne ; Lingman, Markus ; Undén, Johan LU and Nygren, Jens M.
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Covid-19, HR-Qol, perception of illness, post-covid, symptoms
- in
- Infectious Diseases
- volume
- 55
- issue
- 4
- pages
- 272 - 281
- publisher
- Informa Healthcare
- external identifiers
-
- scopus:85147779083
- pmid:36755472
- ISSN
- 2374-4235
- DOI
- 10.1080/23744235.2023.2175904
- language
- English
- LU publication?
- yes
- id
- bef97990-c8f0-4cad-a099-c19a217ea800
- date added to LUP
- 2023-02-23 15:37:12
- date last changed
- 2024-06-14 00:13:18
@article{bef97990-c8f0-4cad-a099-c19a217ea800,
abstract = {{<p>Background: The vast majority of covid-19 patients experience non-severe disease. Nonetheless, long-term symptoms may be common and the impact on quality of life is uncertain. This study aims to examine these aspects in a prospective, longitudinal cohort. Methods: Non-hospitalised patients with PCR-confirmed covid-19 were prospectively invited to self-report assessments of background data, symptoms and recovery, illness perception (BIPQ) and health-related quality of life (HR-Qol) measured by EQ5D-VAS. Results: 154 patients were included (mean age 46 years, 69% female). The majority of participants (65%) had symptoms for 1–4 weeks and 12% more than 6 months. The most common symptoms were initially malaise, fatigue, headache, fever and cough and the most common long-term symptoms were impaired physical condition, fatigue, anosmia and headache. The BIPQ index had a negative correlation with the EQ5D-VAS score after the infection, but not with long-term symptoms. Mean differences in the EQ5D-VAS score were significantly lower after the infection and patients with long-term symptoms had a more pronounced negative effect in EQ5D-VAS scores. Conclusion: We found that most patients with non-severe covid-19 reported symptoms for 1–4 weeks and approximately 10% developed long-term symptoms. Non-severe covid-19 seems to have a negative influence on HR-Qol, especially in patients with long-term symptoms and with a greater burden from the disease. None of the initial symptoms could predict the presence of long-term symptoms.</p>}},
author = {{Löfström, Emma and Kunkel, Stefan and Kötz, Arne and Lingman, Markus and Undén, Johan and Nygren, Jens M.}},
issn = {{2374-4235}},
keywords = {{Covid-19; HR-Qol; perception of illness; post-covid; symptoms}},
language = {{eng}},
number = {{4}},
pages = {{272--281}},
publisher = {{Informa Healthcare}},
series = {{Infectious Diseases}},
title = {{Health-related quality of life and long-term symptoms among patients with non-severe covid-19–a prospective cohort study}},
url = {{http://dx.doi.org/10.1080/23744235.2023.2175904}},
doi = {{10.1080/23744235.2023.2175904}},
volume = {{55}},
year = {{2023}},
}