Role of Tobacco Use in the Etiology of Acoustic Neuroma
Palmisano, Sadie ; Schwartzbaum, Judith ; Prochazka, Michaela ; Pettersson, David ; Bergenheim, Tommy ; Florentzson, Rut ; Harder, Henrik ; Mathiesen, Tiit ; Nyberg, Gunnar and Siesjö, Peter LU
, et al.
(2012)
In American Journal of Epidemiology
175(12).
p.1243-1251
- Abstract
- Two previous studies suggest that cigarette smoking reduces acoustic neuroma risk; however, an association between use of snuff tobacco and acoustic neuroma has not been investigated previously. The authors conducted a case-control study in Sweden from 2002 to 2007, in which 451 cases and 710 population-based controls completed questionnaires. Cases and controls were matched on gender, region, and age within 5 years. The authors estimated odds ratios using conditional logistic regression analyses, adjusted for education and tobacco use (snuff use in the smoking analysis and smoking in the snuff analysis). The risk of acoustic neuroma was greatly reduced in male current smokers (odds ratio (OR) = 0.41, 95% confidence interval (CI): 0.23,... (More)
- Two previous studies suggest that cigarette smoking reduces acoustic neuroma risk; however, an association between use of snuff tobacco and acoustic neuroma has not been investigated previously. The authors conducted a case-control study in Sweden from 2002 to 2007, in which 451 cases and 710 population-based controls completed questionnaires. Cases and controls were matched on gender, region, and age within 5 years. The authors estimated odds ratios using conditional logistic regression analyses, adjusted for education and tobacco use (snuff use in the smoking analysis and smoking in the snuff analysis). The risk of acoustic neuroma was greatly reduced in male current smokers (odds ratio (OR) = 0.41, 95% confidence interval (CI): 0.23, 0.74) and moderately reduced in female current smokers (OR = 0.70, 95% CI: 0.40, 1.23). In contrast, current snuff use among males was not associated with risk of acoustic neuroma (OR = 0.94, 95% CI: 0.57, 1.55). The authors' findings are consistent with previous reports of lower acoustic neuroma risk among current cigarette smokers than among never smokers. The absence of an association between snuff use and acoustic neuroma suggests that some constituent of tobacco smoke other than nicotine may confer protection against acoustic neuroma. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2887442
- author
- Palmisano, Sadie
; Schwartzbaum, Judith
; Prochazka, Michaela
; Pettersson, David
; Bergenheim, Tommy
; Florentzson, Rut
; Harder, Henrik
; Mathiesen, Tiit
; Nyberg, Gunnar
and Siesjö, Peter
LU
, et al. (More)
- Palmisano, Sadie
; Schwartzbaum, Judith
; Prochazka, Michaela
; Pettersson, David
; Bergenheim, Tommy
; Florentzson, Rut
; Harder, Henrik
; Mathiesen, Tiit
; Nyberg, Gunnar
; Siesjö, Peter
LU
and Feychting, Maria
(Less)
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- vestibular schwannoma, tobacco, Swedish, snus, snuff, smoking, acoustic neuroma, cigarette smoking
- in
- American Journal of Epidemiology
- volume
- 175
- issue
- 12
- pages
- 1243 - 1251
- publisher
- Oxford University Press
- external identifiers
-
- wos:000305419400005
- scopus:84862504913
- pmid:22517809
- ISSN
- 0002-9262
- DOI
- 10.1093/aje/kwr465
- language
- English
- LU publication?
- yes
- id
- bf574d85-5503-4338-be7e-db16eb8f1df1 (old id 2887442)
- date added to LUP
- 2016-04-01 10:11:09
- date last changed
- 2025-04-04 15:47:36
@article{bf574d85-5503-4338-be7e-db16eb8f1df1,
abstract = {{Two previous studies suggest that cigarette smoking reduces acoustic neuroma risk; however, an association between use of snuff tobacco and acoustic neuroma has not been investigated previously. The authors conducted a case-control study in Sweden from 2002 to 2007, in which 451 cases and 710 population-based controls completed questionnaires. Cases and controls were matched on gender, region, and age within 5 years. The authors estimated odds ratios using conditional logistic regression analyses, adjusted for education and tobacco use (snuff use in the smoking analysis and smoking in the snuff analysis). The risk of acoustic neuroma was greatly reduced in male current smokers (odds ratio (OR) = 0.41, 95% confidence interval (CI): 0.23, 0.74) and moderately reduced in female current smokers (OR = 0.70, 95% CI: 0.40, 1.23). In contrast, current snuff use among males was not associated with risk of acoustic neuroma (OR = 0.94, 95% CI: 0.57, 1.55). The authors' findings are consistent with previous reports of lower acoustic neuroma risk among current cigarette smokers than among never smokers. The absence of an association between snuff use and acoustic neuroma suggests that some constituent of tobacco smoke other than nicotine may confer protection against acoustic neuroma.}},
author = {{Palmisano, Sadie and Schwartzbaum, Judith and Prochazka, Michaela and Pettersson, David and Bergenheim, Tommy and Florentzson, Rut and Harder, Henrik and Mathiesen, Tiit and Nyberg, Gunnar and Siesjö, Peter and Feychting, Maria}},
issn = {{0002-9262}},
keywords = {{vestibular schwannoma; tobacco; Swedish; snus; snuff; smoking; acoustic neuroma; cigarette smoking}},
language = {{eng}},
number = {{12}},
pages = {{1243--1251}},
publisher = {{Oxford University Press}},
series = {{American Journal of Epidemiology}},
title = {{Role of Tobacco Use in the Etiology of Acoustic Neuroma}},
url = {{http://dx.doi.org/10.1093/aje/kwr465}},
doi = {{10.1093/aje/kwr465}},
volume = {{175}},
year = {{2012}},
}