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Congenital Heart Disease and Its Impact on the Development of Anastomotic Strictures after Reconstruction of Esophageal Atresia

Stenström, Pernilla LU ; Salö, Martin LU ; Anderberg, Magnus LU and Arnbjörnsson, Einar LU (2018) In Gastroenterology Research and Practice 2018.
Abstract

Background: The aim was to explore if severe congenital heart disease (CHD) influenced the need for dilatation of anastomotic strictures (AS) after the repair of esophageal atresia (EA).

Methods: A retrospective case-control study was conducted examining AS in children with EA and Gross type C. The spectra of CHD and cardiac interventions were reviewed. The frequency of dilatations of AS during the first year following EA reconstruction was compared between children with and without severe CHD requiring cardiac surgery during their first year of life. Endoscopic signs of stricture were an indication for dilatation.

Results: Included in the follow-up for AS were 94 patients who had EA reconstructions, of whom 10 (11%)... (More)

Background: The aim was to explore if severe congenital heart disease (CHD) influenced the need for dilatation of anastomotic strictures (AS) after the repair of esophageal atresia (EA).

Methods: A retrospective case-control study was conducted examining AS in children with EA and Gross type C. The spectra of CHD and cardiac interventions were reviewed. The frequency of dilatations of AS during the first year following EA reconstruction was compared between children with and without severe CHD requiring cardiac surgery during their first year of life. Endoscopic signs of stricture were an indication for dilatation.

Results: Included in the follow-up for AS were 94 patients who had EA reconstructions, of whom 10 (11%) children had severe CHD requiring surgery during the first year including 19 different cardiac interventions. In total, 38 patients needed dilatation of esophageal AS, distributed as six (60%) with severe CHD and 32 (38%) without severe CHD (p = 0.31).

Conclusion: Severe CHD was present in 11% of children with EA. Esophageal AS developed in 60% children with concomitant CHD, but although high, it did not reach statistical difference from children without CHD (38%).

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Gastroenterology Research and Practice
volume
2018
article number
6021014
pages
5 pages
publisher
Hindawi Limited
external identifiers
  • scopus:85059139762
  • pmid:29887883
ISSN
1687-6121
DOI
10.1155/2018/6021014
language
English
LU publication?
yes
id
bf8dad75-2d49-4f90-be84-4df941ce55af
date added to LUP
2018-10-11 18:14:47
date last changed
2021-10-03 04:33:01
@article{bf8dad75-2d49-4f90-be84-4df941ce55af,
  abstract     = {<p>Background: The aim was to explore if severe congenital heart disease (CHD) influenced the need for dilatation of anastomotic strictures (AS) after the repair of esophageal atresia (EA).</p><p>Methods: A retrospective case-control study was conducted examining AS in children with EA and Gross type C. The spectra of CHD and cardiac interventions were reviewed. The frequency of dilatations of AS during the first year following EA reconstruction was compared between children with and without severe CHD requiring cardiac surgery during their first year of life. Endoscopic signs of stricture were an indication for dilatation.</p><p>Results: Included in the follow-up for AS were 94 patients who had EA reconstructions, of whom 10 (11%) children had severe CHD requiring surgery during the first year including 19 different cardiac interventions. In total, 38 patients needed dilatation of esophageal AS, distributed as six (60%) with severe CHD and 32 (38%) without severe CHD (p = 0.31).</p><p>Conclusion: Severe CHD was present in 11% of children with EA. Esophageal AS developed in 60% children with concomitant CHD, but although high, it did not reach statistical difference from children without CHD (38%).</p>},
  author       = {Stenström, Pernilla and Salö, Martin and Anderberg, Magnus and Arnbjörnsson, Einar},
  issn         = {1687-6121},
  language     = {eng},
  publisher    = {Hindawi Limited},
  series       = {Gastroenterology Research and Practice},
  title        = {Congenital Heart Disease and Its Impact on the Development of Anastomotic Strictures after Reconstruction of Esophageal Atresia},
  url          = {http://dx.doi.org/10.1155/2018/6021014},
  doi          = {10.1155/2018/6021014},
  volume       = {2018},
  year         = {2018},
}