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Shaping acoustofluidic landscapes to profile and separate cells and sub-micron particles

Augustsson, Per LU (2017) 2017 IEEE International Ultrasonics Symposium, IUS 2017
Abstract

Acoustophoresis, where flow and acoustic fields are used to separate suspended objects, is getting increasingly more attention for cell and bacteria-handling applications relating to medicine and biology. Major benefits are flexibility in design, gentleness to cells and that relatively large forces can be exerted on suspended objects compared to competing technologies. Two important features limit acoustophoresis. First, the strong size dependency hampers separation of cells based on the underlying properties density and compressibility. Second, the presence of acoustic streaming introduces a lower size limit of objects that can be manipulated by primary radiation forces. To address these problems, we explore the action of acoustic... (More)

Acoustophoresis, where flow and acoustic fields are used to separate suspended objects, is getting increasingly more attention for cell and bacteria-handling applications relating to medicine and biology. Major benefits are flexibility in design, gentleness to cells and that relatively large forces can be exerted on suspended objects compared to competing technologies. Two important features limit acoustophoresis. First, the strong size dependency hampers separation of cells based on the underlying properties density and compressibility. Second, the presence of acoustic streaming introduces a lower size limit of objects that can be manipulated by primary radiation forces. To address these problems, we explore the action of acoustic fields on liquids of inhomogeneous acoustic properties which introduce stabilizing forces in the bulk.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
2017 IEEE International Ultrasonics Symposium, IUS 2017
publisher
IEEE Computer Society
conference name
2017 IEEE International Ultrasonics Symposium, IUS 2017
conference location
Washington, United States
conference dates
2017-09-06 - 2017-09-09
external identifiers
  • scopus:85039459590
ISBN
9781538633830
DOI
10.1109/ULTSYM.2017.8091549
language
English
LU publication?
yes
id
c12aac19-4d42-40ff-8a6f-fdaecca0eb69
date added to LUP
2018-01-08 11:57:09
date last changed
2018-11-21 21:37:10
@inproceedings{c12aac19-4d42-40ff-8a6f-fdaecca0eb69,
  abstract     = {<p>Acoustophoresis, where flow and acoustic fields are used to separate suspended objects, is getting increasingly more attention for cell and bacteria-handling applications relating to medicine and biology. Major benefits are flexibility in design, gentleness to cells and that relatively large forces can be exerted on suspended objects compared to competing technologies. Two important features limit acoustophoresis. First, the strong size dependency hampers separation of cells based on the underlying properties density and compressibility. Second, the presence of acoustic streaming introduces a lower size limit of objects that can be manipulated by primary radiation forces. To address these problems, we explore the action of acoustic fields on liquids of inhomogeneous acoustic properties which introduce stabilizing forces in the bulk.</p>},
  author       = {Augustsson, Per},
  isbn         = {9781538633830},
  language     = {eng},
  location     = {Washington, United States},
  month        = {10},
  publisher    = {IEEE Computer Society},
  title        = {Shaping acoustofluidic landscapes to profile and separate cells and sub-micron particles},
  url          = {http://dx.doi.org/10.1109/ULTSYM.2017.8091549},
  year         = {2017},
}