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Increased Rates of Gold and Acrylate Allergy in Individuals with Fibromyalgia Tested with an Extended Dental Patch Test Series

Hopkins, Katharine LU orcid ; Antelmi, Annarita LU ; Dahlin, Jakob LU ; Olsson, Karin ; Svedman, Cecilia LU ; Åstrand, Jacqueline and Bruze, Magnus LU (2023) In Acta Dermato-Venereologica 103.
Abstract

Fibromyalgia is a common chronic pain condition. Rates of contact allergy in individuals with fibromyalgia have not been widely studied. Systemic contact allergy can present with muscle and joint pain and general malaise. The aim of this study is to investigate contact allergy rates in individuals with fibromyalgia to the sensitizers in an extended dental series and compare with control groups. Contact allergy to gold was significantly more common in the fibromyalgia group than the dermatitis control group. When corrected for patch test system, contact allergy to gold was significantly more common in the fibromyalgia group than the dental control group. Contact allergy to hydroxyethyl methacrylate and grouped acrylates and methacrylates... (More)

Fibromyalgia is a common chronic pain condition. Rates of contact allergy in individuals with fibromyalgia have not been widely studied. Systemic contact allergy can present with muscle and joint pain and general malaise. The aim of this study is to investigate contact allergy rates in individuals with fibromyalgia to the sensitizers in an extended dental series and compare with control groups. Contact allergy to gold was significantly more common in the fibromyalgia group than the dermatitis control group. When corrected for patch test system, contact allergy to gold was significantly more common in the fibromyalgia group than the dental control group. Contact allergy to hydroxyethyl methacrylate and grouped acrylates and methacrylates was significantly more common in the fibromyalgia group than the dental control group. In conclusion, individuals with fibromyalgia may have a propensity to sensitization to gold, either via an increased exposure or an alteration in the oral environment. Gold is also implicated in systemic contact dermatitis and may be a factor in elicitation of symptoms in individuals with fibromyalgia. Acrylate allergy is also common in the fibromyalgia population and may be a consequence of occupational exposure or dental treatment.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
acrylates, contact allergy, delayed hypersensitivity, fibromyalgia, gold, systemic contact allergy
in
Acta Dermato-Venereologica
volume
103
article number
adv22336
publisher
Medical Journals Limited
external identifiers
  • pmid:38078690
  • scopus:85179321475
ISSN
0001-5555
DOI
10.2340/actadv.v103.22336
language
English
LU publication?
yes
id
c180c5cc-7796-42b6-9cd9-ac80db5733ac
date added to LUP
2024-01-11 13:02:25
date last changed
2024-04-12 06:53:59
@article{c180c5cc-7796-42b6-9cd9-ac80db5733ac,
  abstract     = {{<p>Fibromyalgia is a common chronic pain condition. Rates of contact allergy in individuals with fibromyalgia have not been widely studied. Systemic contact allergy can present with muscle and joint pain and general malaise. The aim of this study is to investigate contact allergy rates in individuals with fibromyalgia to the sensitizers in an extended dental series and compare with control groups. Contact allergy to gold was significantly more common in the fibromyalgia group than the dermatitis control group. When corrected for patch test system, contact allergy to gold was significantly more common in the fibromyalgia group than the dental control group. Contact allergy to hydroxyethyl methacrylate and grouped acrylates and methacrylates was significantly more common in the fibromyalgia group than the dental control group. In conclusion, individuals with fibromyalgia may have a propensity to sensitization to gold, either via an increased exposure or an alteration in the oral environment. Gold is also implicated in systemic contact dermatitis and may be a factor in elicitation of symptoms in individuals with fibromyalgia. Acrylate allergy is also common in the fibromyalgia population and may be a consequence of occupational exposure or dental treatment.</p>}},
  author       = {{Hopkins, Katharine and Antelmi, Annarita and Dahlin, Jakob and Olsson, Karin and Svedman, Cecilia and Åstrand, Jacqueline and Bruze, Magnus}},
  issn         = {{0001-5555}},
  keywords     = {{acrylates; contact allergy; delayed hypersensitivity; fibromyalgia; gold; systemic contact allergy}},
  language     = {{eng}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Increased Rates of Gold and Acrylate Allergy in Individuals with Fibromyalgia Tested with an Extended Dental Patch Test Series}},
  url          = {{http://dx.doi.org/10.2340/actadv.v103.22336}},
  doi          = {{10.2340/actadv.v103.22336}},
  volume       = {{103}},
  year         = {{2023}},
}