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Pseudomyxoma peritonei; een zeldzame tumor, te behandelen met cytoreductieve chirurgie en hypertherme intraperitoneale chemotherapie

Smeenk, R. M. ; Verwaal, V. J. LU and Zoetmulder, F. A.N. (2007) In Nederlands Tijdschrift voor Geneeskunde 151(7). p.418-423
Abstract

Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after initial treatment, the second patient had died of disease progression but the other two were alive and free of disease. Pseudomyxoma peritonei is a rare disease, characterised by progressive intraperitoneal accumulation of mucinous ascites, produced by a mucinous tumour mass on the peritoneal surfaces. The primary tumour is usually a mucinous... (More)

Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after initial treatment, the second patient had died of disease progression but the other two were alive and free of disease. Pseudomyxoma peritonei is a rare disease, characterised by progressive intraperitoneal accumulation of mucinous ascites, produced by a mucinous tumour mass on the peritoneal surfaces. The primary tumour is usually a mucinous adenoma of the appendix. Treatment by cytoreductive surgery and HIPEC can result in a 5-year survival rate of more than 80%, depending on the histopathology and the completeness of the cytoreduction. Recognising pseudomyxoma peritonei in an early stage, when complete cytoreduction is still achievable, may result in a considerable improvement in survival.

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author
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alternative title
Pseudomyxoma peritonei; a rare tumour that can be treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Antineoplastic Agents/therapeutic use, Combined Modality Therapy, Fatal Outcome, Female, Humans, Hyperthermia, Induced/methods, Male, Middle Aged, Peritoneal Neoplasms/diagnosis, Pseudomyxoma Peritonei/diagnosis, Treatment Outcome
in
Nederlands Tijdschrift voor Geneeskunde
volume
151
issue
7
pages
6 pages
publisher
Bohn Stafleu van Loghum
external identifiers
  • pmid:17343142
  • scopus:33847384541
ISSN
0028-2162
language
Dutch
LU publication?
no
additional info
Original language: Dutch
id
c2795361-1c5d-4ce6-8b6e-e2bf0844205f
date added to LUP
2022-04-12 09:52:54
date last changed
2024-01-06 23:51:15
@article{c2795361-1c5d-4ce6-8b6e-e2bf0844205f,
  abstract     = {{<p>Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after initial treatment, the second patient had died of disease progression but the other two were alive and free of disease. Pseudomyxoma peritonei is a rare disease, characterised by progressive intraperitoneal accumulation of mucinous ascites, produced by a mucinous tumour mass on the peritoneal surfaces. The primary tumour is usually a mucinous adenoma of the appendix. Treatment by cytoreductive surgery and HIPEC can result in a 5-year survival rate of more than 80%, depending on the histopathology and the completeness of the cytoreduction. Recognising pseudomyxoma peritonei in an early stage, when complete cytoreduction is still achievable, may result in a considerable improvement in survival.</p>}},
  author       = {{Smeenk, R. M. and Verwaal, V. J. and Zoetmulder, F. A.N.}},
  issn         = {{0028-2162}},
  keywords     = {{Adult; Antineoplastic Agents/therapeutic use; Combined Modality Therapy; Fatal Outcome; Female; Humans; Hyperthermia, Induced/methods; Male; Middle Aged; Peritoneal Neoplasms/diagnosis; Pseudomyxoma Peritonei/diagnosis; Treatment Outcome}},
  language     = {{dut}},
  month        = {{02}},
  number       = {{7}},
  pages        = {{418--423}},
  publisher    = {{Bohn Stafleu van Loghum}},
  series       = {{Nederlands Tijdschrift voor Geneeskunde}},
  title        = {{Pseudomyxoma peritonei; een zeldzame tumor, te behandelen met cytoreductieve chirurgie en hypertherme intraperitoneale chemotherapie}},
  volume       = {{151}},
  year         = {{2007}},
}