A national study of health-related quality of life in patients with cancer of the base of the tongue compared to the general population and to patients with tonsillar carcinoma
(2021) In Head and Neck 43(12). p.3843-3856- Abstract
Background: This exploratory, registry-based, cross-sectional study aimed to evaluate patients' health-related quality of life (HRQOL) in a subsite of oropharyngeal cancer: cancer of the base of the tongue (CBT). Methods: CBT patients, treated with curative intent, completed the EORTC QLQ-C30 and QLQ-H&N35 questionnaires 15 months after diagnosis. The HRQOL of CBT patients was compared to reference scores from the general population and to that of tonsillar carcinoma patients. Results: The 190 CBT patients scored significantly worse than members of the general population on most scales. CBT patients with human papilloma virus (HPV)-positive tumors had significantly better HRQOL on 8 of 28 scales than HPV-negative patients. Compared... (More)
Background: This exploratory, registry-based, cross-sectional study aimed to evaluate patients' health-related quality of life (HRQOL) in a subsite of oropharyngeal cancer: cancer of the base of the tongue (CBT). Methods: CBT patients, treated with curative intent, completed the EORTC QLQ-C30 and QLQ-H&N35 questionnaires 15 months after diagnosis. The HRQOL of CBT patients was compared to reference scores from the general population and to that of tonsillar carcinoma patients. Results: The 190 CBT patients scored significantly worse than members of the general population on most scales. CBT patients with human papilloma virus (HPV)-positive tumors had significantly better HRQOL on 8 of 28 scales than HPV-negative patients. Compared to 405 tonsillar carcinoma patients, CBT patients had significantly worse HRQOL on 8 of the 28 scales, the majority local head and neck related problems. Conclusion: One year after treatment, CBT patients' HRQOL was significantly worse in many areas compared to that of the general population and slightly worse than that of tonsillar carcinoma patients.
(Less)
- author
- author collaboration
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cancer of the base of the tongue, head-and-neck cancer, human papillomavirus, oropharyngeal cancer, quality-of-life
- in
- Head and Neck
- volume
- 43
- issue
- 12
- pages
- 3843 - 3856
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85115841892
- pmid:34558771
- ISSN
- 1043-3074
- DOI
- 10.1002/hed.26882
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2021 Wiley Periodicals LLC.
- id
- c399ef35-136d-461c-91bf-e183c6c1dcf4
- date added to LUP
- 2021-10-20 10:33:35
- date last changed
- 2024-06-15 18:29:05
@article{c399ef35-136d-461c-91bf-e183c6c1dcf4, abstract = {{<p>Background: This exploratory, registry-based, cross-sectional study aimed to evaluate patients' health-related quality of life (HRQOL) in a subsite of oropharyngeal cancer: cancer of the base of the tongue (CBT). Methods: CBT patients, treated with curative intent, completed the EORTC QLQ-C30 and QLQ-H&N35 questionnaires 15 months after diagnosis. The HRQOL of CBT patients was compared to reference scores from the general population and to that of tonsillar carcinoma patients. Results: The 190 CBT patients scored significantly worse than members of the general population on most scales. CBT patients with human papilloma virus (HPV)-positive tumors had significantly better HRQOL on 8 of 28 scales than HPV-negative patients. Compared to 405 tonsillar carcinoma patients, CBT patients had significantly worse HRQOL on 8 of the 28 scales, the majority local head and neck related problems. Conclusion: One year after treatment, CBT patients' HRQOL was significantly worse in many areas compared to that of the general population and slightly worse than that of tonsillar carcinoma patients.</p>}}, author = {{Berg, Malin and Adnan, Ali and Högmo, Anders and Sjödin, Helena and Gebre-Medhin, Maria and Laurell, Göran and Reizenstein, Johan and Farnebo, Lovisa and Norberg, Lena Spaak and Notstam, Isak and Holmberg, Erik and Cange, Hedda Haugen and Hammerlid, Eva}}, issn = {{1043-3074}}, keywords = {{cancer of the base of the tongue; head-and-neck cancer; human papillomavirus; oropharyngeal cancer; quality-of-life}}, language = {{eng}}, number = {{12}}, pages = {{3843--3856}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Head and Neck}}, title = {{A national study of health-related quality of life in patients with cancer of the base of the tongue compared to the general population and to patients with tonsillar carcinoma}}, url = {{http://dx.doi.org/10.1002/hed.26882}}, doi = {{10.1002/hed.26882}}, volume = {{43}}, year = {{2021}}, }