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What is a Bladder Cancer Molecular Subtype?

Höglund, Mattias LU (2023) In Bladder Cancer 9(4). p.293-298
Abstract

BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assumptions when defining molecular subtypes. METHODS: To critically reflect on some of the principles and methods used when defining molecular subtypes. RESULTS: Depending on underlying assumptions and aims for the definitions of subtypes, different types of molecular subtypes will be arrived at. CONCLUSION: The underlying assumptions and their... (More)

BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assumptions when defining molecular subtypes. METHODS: To critically reflect on some of the principles and methods used when defining molecular subtypes. RESULTS: Depending on underlying assumptions and aims for the definitions of subtypes, different types of molecular subtypes will be arrived at. CONCLUSION: The underlying assumptions and their consequences must be better clarified when defining molecular subtypes.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bladder Cancer
volume
9
issue
4
pages
6 pages
publisher
IOS Press
external identifiers
  • scopus:85180298180
ISSN
2352-3727
DOI
10.3233/BLC-220124
language
English
LU publication?
yes
id
c3cc90e8-883f-455f-8e8e-867d4dd49d43
date added to LUP
2024-01-03 12:08:09
date last changed
2024-01-03 12:09:26
@article{c3cc90e8-883f-455f-8e8e-867d4dd49d43,
  abstract     = {{<p>BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assumptions when defining molecular subtypes. METHODS: To critically reflect on some of the principles and methods used when defining molecular subtypes. RESULTS: Depending on underlying assumptions and aims for the definitions of subtypes, different types of molecular subtypes will be arrived at. CONCLUSION: The underlying assumptions and their consequences must be better clarified when defining molecular subtypes.</p>}},
  author       = {{Höglund, Mattias}},
  issn         = {{2352-3727}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{293--298}},
  publisher    = {{IOS Press}},
  series       = {{Bladder Cancer}},
  title        = {{What is a Bladder Cancer Molecular Subtype?}},
  url          = {{http://dx.doi.org/10.3233/BLC-220124}},
  doi          = {{10.3233/BLC-220124}},
  volume       = {{9}},
  year         = {{2023}},
}