Helicobacter pylori : Is it Transmitted Through Faecal-oral or Oral-oral Route?
(2013) In Journal of Pure and Applied Microbiology 7(3). p.2429-2438- Abstract
- The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of patients who were suffering from upper GI complaints. These patients resided in Mumbai city, India. Clinical specimens from different sources were subjected to RUT, Culture, Histopathology and Polymerase chain reaction (PCR). We found H. pylori in antral biopsies and faeces by culture and PCR but absent in dental plaques. Therefore, faecal-oral... (More)
- The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of patients who were suffering from upper GI complaints. These patients resided in Mumbai city, India. Clinical specimens from different sources were subjected to RUT, Culture, Histopathology and Polymerase chain reaction (PCR). We found H. pylori in antral biopsies and faeces by culture and PCR but absent in dental plaques. Therefore, faecal-oral is the possible route of transmission of this bacterium. Dental plaque may not be a permanent reservoir of this bacterium because this organism needs strict microaerophilic conditions to survive. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4204088
- author
- Mulchandani, Rupa ; Nilsson, Hans-Olof LU ; Wadström, Torkel LU and Joshi, B. R.
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Helicobacter pylori, PCR, faeces, HPU, VacA, CagA
- in
- Journal of Pure and Applied Microbiology
- volume
- 7
- issue
- 3
- pages
- 2429 - 2438
- publisher
- DR M N KHAN
- external identifiers
-
- wos:000326482600117
- scopus:84888778648
- ISSN
- 0973-7510
- language
- English
- LU publication?
- yes
- id
- c3ee3c47-2270-49b2-938e-5fc0df0a634c (old id 4204088)
- date added to LUP
- 2016-04-01 13:55:18
- date last changed
- 2022-01-27 21:49:23
@article{c3ee3c47-2270-49b2-938e-5fc0df0a634c, abstract = {{The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of patients who were suffering from upper GI complaints. These patients resided in Mumbai city, India. Clinical specimens from different sources were subjected to RUT, Culture, Histopathology and Polymerase chain reaction (PCR). We found H. pylori in antral biopsies and faeces by culture and PCR but absent in dental plaques. Therefore, faecal-oral is the possible route of transmission of this bacterium. Dental plaque may not be a permanent reservoir of this bacterium because this organism needs strict microaerophilic conditions to survive.}}, author = {{Mulchandani, Rupa and Nilsson, Hans-Olof and Wadström, Torkel and Joshi, B. R.}}, issn = {{0973-7510}}, keywords = {{Helicobacter pylori; PCR; faeces; HPU; VacA; CagA}}, language = {{eng}}, number = {{3}}, pages = {{2429--2438}}, publisher = {{DR M N KHAN}}, series = {{Journal of Pure and Applied Microbiology}}, title = {{Helicobacter pylori : Is it Transmitted Through Faecal-oral or Oral-oral Route?}}, volume = {{7}}, year = {{2013}}, }