X-ray spectroscopy and imaging of selenium in living systems
(2018) In Biochimica et Biophysica Acta. General Subjects 1862(11). p.2383-2392- Abstract
BACKGROUND: Selenium is an essential element with a rich and varied chemistry in living organisms. It plays a variety of important roles ranging from being essential in enzymes that are critical for redox homeostasis to acting as a deterrent for herbivory in hyperaccumulating plants. Despite its importance there are many open questions, especially related to its chemistry in situ within living organisms.
SCOPE OF REVIEW: This review discusses X-ray spectroscopy and imaging of selenium in biological samples, with an emphasis on the methods, and in particular the techniques of X-ray absorption spectroscopy (XAS) and X-ray fluorescence imaging (XFI). We discuss the experimental methods and capabilities of XAS and XFI, and review... (More)
BACKGROUND: Selenium is an essential element with a rich and varied chemistry in living organisms. It plays a variety of important roles ranging from being essential in enzymes that are critical for redox homeostasis to acting as a deterrent for herbivory in hyperaccumulating plants. Despite its importance there are many open questions, especially related to its chemistry in situ within living organisms.
SCOPE OF REVIEW: This review discusses X-ray spectroscopy and imaging of selenium in biological samples, with an emphasis on the methods, and in particular the techniques of X-ray absorption spectroscopy (XAS) and X-ray fluorescence imaging (XFI). We discuss the experimental methods and capabilities of XAS and XFI, and review their advantages and their limitations. A perspective on future possibilities and next-generation of experiments is also provided.
MAJOR CONCLUSIONS: XAS and XFI provide powerful probes of selenium chemistry, together with unique in situ capabilities. The opportunities and capabilities of the next generation of advanced X-ray spectroscopy experiments are particularly exciting.
GENERAL SIGNIFICANCE: XAS and XFI provide versatile tools that are generally applicable to any element with a convenient X-ray absorption edge, suitable for investigating complex systems essentially without pre-treatment.
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- author
- Dolgova, Natalia V ; Nehzati, Susan LU ; Choudhury, Sanjukta ; MacDonald, Tracy C ; Regnier, Nathan R ; Crawford, Andrew M ; Ponomarenko, Olena ; George, Graham N and Pickering, Ingrid J
- publishing date
- 2018-05-03
- type
- Contribution to journal
- publication status
- published
- in
- Biochimica et Biophysica Acta. General Subjects
- volume
- 1862
- issue
- 11
- pages
- 2383 - 2392
- publisher
- Elsevier
- external identifiers
-
- pmid:29729308
- scopus:85046825959
- ISSN
- 0304-4165
- DOI
- 10.1016/j.bbagen.2018.04.024
- language
- English
- LU publication?
- no
- additional info
- Copyright © 2018. Published by Elsevier B.V.
- id
- c4379641-fba3-4ca7-a3e4-7b23b7ac4e90
- date added to LUP
- 2020-02-07 14:44:27
- date last changed
- 2024-01-16 21:29:03
@article{c4379641-fba3-4ca7-a3e4-7b23b7ac4e90,
abstract = {{<p>BACKGROUND: Selenium is an essential element with a rich and varied chemistry in living organisms. It plays a variety of important roles ranging from being essential in enzymes that are critical for redox homeostasis to acting as a deterrent for herbivory in hyperaccumulating plants. Despite its importance there are many open questions, especially related to its chemistry in situ within living organisms.</p><p>SCOPE OF REVIEW: This review discusses X-ray spectroscopy and imaging of selenium in biological samples, with an emphasis on the methods, and in particular the techniques of X-ray absorption spectroscopy (XAS) and X-ray fluorescence imaging (XFI). We discuss the experimental methods and capabilities of XAS and XFI, and review their advantages and their limitations. A perspective on future possibilities and next-generation of experiments is also provided.</p><p>MAJOR CONCLUSIONS: XAS and XFI provide powerful probes of selenium chemistry, together with unique in situ capabilities. The opportunities and capabilities of the next generation of advanced X-ray spectroscopy experiments are particularly exciting.</p><p>GENERAL SIGNIFICANCE: XAS and XFI provide versatile tools that are generally applicable to any element with a convenient X-ray absorption edge, suitable for investigating complex systems essentially without pre-treatment.</p>}},
author = {{Dolgova, Natalia V and Nehzati, Susan and Choudhury, Sanjukta and MacDonald, Tracy C and Regnier, Nathan R and Crawford, Andrew M and Ponomarenko, Olena and George, Graham N and Pickering, Ingrid J}},
issn = {{0304-4165}},
language = {{eng}},
month = {{05}},
number = {{11}},
pages = {{2383--2392}},
publisher = {{Elsevier}},
series = {{Biochimica et Biophysica Acta. General Subjects}},
title = {{X-ray spectroscopy and imaging of selenium in living systems}},
url = {{http://dx.doi.org/10.1016/j.bbagen.2018.04.024}},
doi = {{10.1016/j.bbagen.2018.04.024}},
volume = {{1862}},
year = {{2018}},
}