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Thermodynamics of binding of alpha-cyclodextrin to straight-chain alkyl derivatives in aqueous solution

Stödeman, Magnus LU ; Gomez-Orellana, I and Hallen, D (2003) In Journal of Inclusion Phenomena and Molecular Recognition in Chemistry 46(3-4). p.125-132
Abstract
Apparent standard Gibbs energy, enthalpy, entropy, and heat capacity data of the interactions of alpha-cyclodextrin (alphaCD) to some n-carboxylates H(CH2)(n)COO- (n = 4 - 6), are determined by isothermal titration microcalorimetry at different temperatures in phosphate buffer, pH 9.0, assuming a 1 : 1 model in dilute solution. Modelling of contributions of the thermodynamic properties of the solution indicates that aCD undergoes conformational change upon binding to homologous series of n-carboxylates, n-alcohols, alpha,omega-alkane dicarboxylates and alpha,omega-alkane diols.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
complex formation, alpha-cyclodextrin, alkyl derivatives, microcalorimetry
in
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry
volume
46
issue
3-4
pages
125 - 132
publisher
Springer
external identifiers
  • wos:000186271000002
  • scopus:3543015016
ISSN
0923-0750
DOI
10.1023/A:1026380832331
language
English
LU publication?
yes
id
c44a1eae-4ace-4bef-a5a9-d665c9cb5704 (old id 297153)
date added to LUP
2016-04-01 15:21:01
date last changed
2022-01-28 04:54:14
@article{c44a1eae-4ace-4bef-a5a9-d665c9cb5704,
  abstract     = {{Apparent standard Gibbs energy, enthalpy, entropy, and heat capacity data of the interactions of alpha-cyclodextrin (alphaCD) to some n-carboxylates H(CH2)(n)COO- (n = 4 - 6), are determined by isothermal titration microcalorimetry at different temperatures in phosphate buffer, pH 9.0, assuming a 1 : 1 model in dilute solution. Modelling of contributions of the thermodynamic properties of the solution indicates that aCD undergoes conformational change upon binding to homologous series of n-carboxylates, n-alcohols, alpha,omega-alkane dicarboxylates and alpha,omega-alkane diols.}},
  author       = {{Stödeman, Magnus and Gomez-Orellana, I and Hallen, D}},
  issn         = {{0923-0750}},
  keywords     = {{complex formation; alpha-cyclodextrin; alkyl derivatives; microcalorimetry}},
  language     = {{eng}},
  number       = {{3-4}},
  pages        = {{125--132}},
  publisher    = {{Springer}},
  series       = {{Journal of Inclusion Phenomena and Molecular Recognition in Chemistry}},
  title        = {{Thermodynamics of binding of alpha-cyclodextrin to straight-chain alkyl derivatives in aqueous solution}},
  url          = {{http://dx.doi.org/10.1023/A:1026380832331}},
  doi          = {{10.1023/A:1026380832331}},
  volume       = {{46}},
  year         = {{2003}},
}