Cervical cancer risk perceptions, sexual risk behaviors and sexually transmitted infections among Bivalent Human Papillomavirus vaccinated and non-vaccinated young women in Uganda - 5 year follow up study
(2017) In BMC Women's Health 17(1). p.1-12- Abstract
Background: Previous studies were conflicting regarding the associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors and STIs. This study compared the HPV-vaccinated and non-vaccinated young women in Uganda regarding cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections 5 years after vaccine implementation. Methods: This was a population-based comparative cross-sectional survey conducted in Uganda. The 438 participants were sexually active young women aged 15-24 years and mean age was 18.6 (SD 1.4). The majority (53.0%) were HPV-vaccinated in 2008 without assessment of sexual activity prior to HPV vaccination. Upon verbal assessment of sexual activity at the... (More)
Background: Previous studies were conflicting regarding the associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors and STIs. This study compared the HPV-vaccinated and non-vaccinated young women in Uganda regarding cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections 5 years after vaccine implementation. Methods: This was a population-based comparative cross-sectional survey conducted in Uganda. The 438 participants were sexually active young women aged 15-24 years and mean age was 18.6 (SD 1.4). The majority (53.0%) were HPV-vaccinated in 2008 without assessment of sexual activity prior to HPV vaccination. Upon verbal assessment of sexual activity at the time of follow-up, data were collected using a questionnaire and laboratory testing of blood samples for syphilis and HIV infections. Results: There were no significant differences between the HPV-vaccinated and non-vaccinated groups regarding the prevalence of high-risk sexual behaviors, syphilis and HIV infections. Cervical cancer risk perceptions and age at sexual debut were nonetheless significantly lower among the vaccinated group compared to their non-vaccinated counterparts. However, HPV vaccination was not significantly associated to cervical cancer risk perceptions and early age at sexual debut in multivariate logistic regression analysis. Conclusions: We found no associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections among young women in Uganda 5 years after vaccine implementation. Young girls in the study population were found to be sexually active at a young age, affirming the importance of targeting girls of younger age for HPV vaccination.
(Less)
- author
- Kumakech, Edward ; Andersson, Sören ; Wabinga, Henry ; Musubika, Caroline ; Kirimunda, Samuel and Berggren, Vanja LU
- organization
- publishing date
- 2017-06-02
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bivalent Human Papillomavirus (HPV) vaccination, Cervical cancer risk perceptions, Sexual risk behaviors, Sexually transmitted infections, Uganda, Young women
- in
- BMC Women's Health
- volume
- 17
- issue
- 1
- article number
- 40
- pages
- 1 - 12
- publisher
- BioMed Central (BMC)
- external identifiers
-
- scopus:85020029260
- pmid:28576143
- wos:000402564800002
- ISSN
- 1472-6874
- DOI
- 10.1186/s12905-017-0394-y
- language
- English
- LU publication?
- yes
- id
- c4cb7701-ae8f-413f-9ddc-27153dfdbce0
- date added to LUP
- 2017-06-19 10:26:30
- date last changed
- 2024-05-26 17:46:37
@article{c4cb7701-ae8f-413f-9ddc-27153dfdbce0,
abstract = {{<p>Background: Previous studies were conflicting regarding the associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors and STIs. This study compared the HPV-vaccinated and non-vaccinated young women in Uganda regarding cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections 5 years after vaccine implementation. Methods: This was a population-based comparative cross-sectional survey conducted in Uganda. The 438 participants were sexually active young women aged 15-24 years and mean age was 18.6 (SD 1.4). The majority (53.0%) were HPV-vaccinated in 2008 without assessment of sexual activity prior to HPV vaccination. Upon verbal assessment of sexual activity at the time of follow-up, data were collected using a questionnaire and laboratory testing of blood samples for syphilis and HIV infections. Results: There were no significant differences between the HPV-vaccinated and non-vaccinated groups regarding the prevalence of high-risk sexual behaviors, syphilis and HIV infections. Cervical cancer risk perceptions and age at sexual debut were nonetheless significantly lower among the vaccinated group compared to their non-vaccinated counterparts. However, HPV vaccination was not significantly associated to cervical cancer risk perceptions and early age at sexual debut in multivariate logistic regression analysis. Conclusions: We found no associations between HPV vaccination, cervical cancer risk perceptions, high-risk sexual behaviors, syphilis and HIV infections among young women in Uganda 5 years after vaccine implementation. Young girls in the study population were found to be sexually active at a young age, affirming the importance of targeting girls of younger age for HPV vaccination.</p>}},
author = {{Kumakech, Edward and Andersson, Sören and Wabinga, Henry and Musubika, Caroline and Kirimunda, Samuel and Berggren, Vanja}},
issn = {{1472-6874}},
keywords = {{Bivalent Human Papillomavirus (HPV) vaccination; Cervical cancer risk perceptions; Sexual risk behaviors; Sexually transmitted infections; Uganda; Young women}},
language = {{eng}},
month = {{06}},
number = {{1}},
pages = {{1--12}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Women's Health}},
title = {{Cervical cancer risk perceptions, sexual risk behaviors and sexually transmitted infections among Bivalent Human Papillomavirus vaccinated and non-vaccinated young women in Uganda - 5 year follow up study}},
url = {{http://dx.doi.org/10.1186/s12905-017-0394-y}},
doi = {{10.1186/s12905-017-0394-y}},
volume = {{17}},
year = {{2017}},
}