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Iso-acoustic focusing for size-insensitive cell separation based on acoustic properties

Augustsson, P. LU and Voldman, J. (2015) 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences p.14-16
Abstract

We report a novel size-insensitive method, iso-acoustic focusing (IAF), that can, for the first time, analyze and separate cells based on their intrinsic acoustic properties. We characterize the IAF system using two different cell lines and apply it to measuring the acoustic impedance of two subgroups of white blood cells (WBC): neutrophils and lymphocytes. We find cell type specific differences in acoustic properties that indicates that this method has potential for cell phenotyping and cell separations.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Acoustophoresis, Blood cells, Cell phenotyping
in
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
pages
3 pages
publisher
Chemical and Biological Microsystems Society
conference name
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
external identifiers
  • scopus:84983358979
ISBN
9780979806483
language
English
LU publication?
yes
id
c4f098d4-4f41-41ce-a0c2-73cd12d3ecda
date added to LUP
2016-12-21 09:01:19
date last changed
2017-05-16 15:43:29
@inproceedings{c4f098d4-4f41-41ce-a0c2-73cd12d3ecda,
  abstract     = {<p>We report a novel size-insensitive method, iso-acoustic focusing (IAF), that can, for the first time, analyze and separate cells based on their intrinsic acoustic properties. We characterize the IAF system using two different cell lines and apply it to measuring the acoustic impedance of two subgroups of white blood cells (WBC): neutrophils and lymphocytes. We find cell type specific differences in acoustic properties that indicates that this method has potential for cell phenotyping and cell separations.</p>},
  author       = {Augustsson, P. and Voldman, J.},
  booktitle    = {MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences},
  isbn         = {9780979806483},
  keyword      = {Acoustophoresis,Blood cells,Cell phenotyping},
  language     = {eng},
  pages        = {14--16},
  publisher    = {Chemical and Biological Microsystems Society},
  title        = {Iso-acoustic focusing for size-insensitive cell separation based on acoustic properties},
  year         = {2015},
}