Iso-acoustic focusing for size-insensitive cell separation based on acoustic properties
(2015) 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 p.14-16- Abstract
We report a novel size-insensitive method, iso-acoustic focusing (IAF), that can, for the first time, analyze and separate cells based on their intrinsic acoustic properties. We characterize the IAF system using two different cell lines and apply it to measuring the acoustic impedance of two subgroups of white blood cells (WBC): neutrophils and lymphocytes. We find cell type specific differences in acoustic properties that indicates that this method has potential for cell phenotyping and cell separations.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/c4f098d4-4f41-41ce-a0c2-73cd12d3ecda
- author
- Augustsson, P. LU and Voldman, J.
- organization
- publishing date
- 2015
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustophoresis, Blood cells, Cell phenotyping
- host publication
- MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- pages
- 3 pages
- publisher
- Chemical and Biological Microsystems Society
- conference name
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
- conference location
- Gyeongju, Korea, Republic of
- conference dates
- 2015-10-25 - 2015-10-29
- external identifiers
-
- scopus:84983358979
- ISBN
- 9780979806483
- language
- English
- LU publication?
- yes
- id
- c4f098d4-4f41-41ce-a0c2-73cd12d3ecda
- date added to LUP
- 2016-12-21 09:01:19
- date last changed
- 2022-01-30 08:43:24
@inproceedings{c4f098d4-4f41-41ce-a0c2-73cd12d3ecda, abstract = {{<p>We report a novel size-insensitive method, iso-acoustic focusing (IAF), that can, for the first time, analyze and separate cells based on their intrinsic acoustic properties. We characterize the IAF system using two different cell lines and apply it to measuring the acoustic impedance of two subgroups of white blood cells (WBC): neutrophils and lymphocytes. We find cell type specific differences in acoustic properties that indicates that this method has potential for cell phenotyping and cell separations.</p>}}, author = {{Augustsson, P. and Voldman, J.}}, booktitle = {{MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences}}, isbn = {{9780979806483}}, keywords = {{Acoustophoresis; Blood cells; Cell phenotyping}}, language = {{eng}}, pages = {{14--16}}, publisher = {{Chemical and Biological Microsystems Society}}, title = {{Iso-acoustic focusing for size-insensitive cell separation based on acoustic properties}}, year = {{2015}}, }