Primary sequence differences between Chido and Rodgers variants of tryptic C4d of the human complement system
(1984) In FEBS Letters 170(2). p.8-254- Abstract
- Human tryptic C4d of the Chido and Rodgers variant was fragmented by cyanogen bromide and trypsin. The fragments were characterized by amino acid analysis and sequence determination. Polymorphism between the two genetic variants was detected in 5 positions. Four were closely located (residues 141, 142, 145, 146), where Leu, Ser, Ile, His occurred in the Chido variant and Pro, Cys, Leu, Asp in the Rodgers variant, respectively. In position 94 Gly was found in Chido and Asp in Rodgers. Alignment of the fragments was performed and it is concluded that tryptic C4d of both variants contains 346 residues.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3965049
- author
- Hellman, U. ; Eggertsen, G. ; Lundwall, Åke LU ; Engstrom, Å. and Sjoquist, J.
- publishing date
- 1984
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Polymorphism, Peptide Fragments/*genetics, Humans, Cyanogen Bromide, *Complement C4b, Complement C4/*genetics, Comparative Study, Amino Acid Sequence, Blood Group Antigens/*genetics, Genetic, Research Support, Non-U.S. Gov't, Trypsin, *Variation (Genetics)
- in
- FEBS Letters
- volume
- 170
- issue
- 2
- pages
- 8 - 254
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0021223752
- ISSN
- 1873-3468
- language
- English
- LU publication?
- no
- additional info
- 2
- id
- c5ce1c5c-6343-4437-86bf-3a6cca3a175a (old id 3965049)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6723966
- date added to LUP
- 2016-04-04 14:13:47
- date last changed
- 2021-01-03 06:42:28
@article{c5ce1c5c-6343-4437-86bf-3a6cca3a175a, abstract = {{Human tryptic C4d of the Chido and Rodgers variant was fragmented by cyanogen bromide and trypsin. The fragments were characterized by amino acid analysis and sequence determination. Polymorphism between the two genetic variants was detected in 5 positions. Four were closely located (residues 141, 142, 145, 146), where Leu, Ser, Ile, His occurred in the Chido variant and Pro, Cys, Leu, Asp in the Rodgers variant, respectively. In position 94 Gly was found in Chido and Asp in Rodgers. Alignment of the fragments was performed and it is concluded that tryptic C4d of both variants contains 346 residues.}}, author = {{Hellman, U. and Eggertsen, G. and Lundwall, Åke and Engstrom, Å. and Sjoquist, J.}}, issn = {{1873-3468}}, keywords = {{Polymorphism; Peptide Fragments/*genetics; Humans; Cyanogen Bromide; *Complement C4b; Complement C4/*genetics; Comparative Study; Amino Acid Sequence; Blood Group Antigens/*genetics; Genetic; Research Support; Non-U.S. Gov't; Trypsin; *Variation (Genetics)}}, language = {{eng}}, number = {{2}}, pages = {{8--254}}, publisher = {{Wiley-Blackwell}}, series = {{FEBS Letters}}, title = {{Primary sequence differences between Chido and Rodgers variants of tryptic C4d of the human complement system}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6723966}}, volume = {{170}}, year = {{1984}}, }