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Interaction between rs10830963 polymorphism in MTNR1B and lifestyle intervention on occurrence of gestational diabetes

Grotenfelt, Nora E.; Wasenius, Niko S.; Rönö, Kristiina; Laivuori, Hannele; Stach-Lempinen, Beata; Orho-Melander, Marju LU ; Schulz, Christina Alexandra LU ; Kautiainen, Hannu; Koivusalo, Saila B. and Eriksson, Johan G. LU (2016) In Diabetologia 59(8). p.1655-1658
Abstract

Aims/hypothesis: The aim of this study was to assess the interaction between melatonin receptor 1B gene (MTNR1B) rs10830963 polymorphism and lifestyle intervention during pregnancy on occurrence of gestational diabetes mellitus (GDM) in high-risk women. Methods: This is a secondary analysis of the randomised controlled gestational diabetes prevention trial ‘RADIEL’, conducted between 2008 and 2014 in four maternity hospitals in southern Finland. A total of 226 women with a history of GDM and/or a pre-pregnancy BMI ≥ 30 kg/m2 were enrolled at

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Clinical trial, Diabetes, Gestational, Melatonin, MT2, Polymorphism, Pregnancy, Prevalence, Public health, Receptor, Single nucleotide
in
Diabetologia
volume
59
issue
8
pages
4 pages
publisher
Springer Verlag
external identifiers
  • scopus:84969835042
  • wos:000379158800011
ISSN
0012-186X
DOI
10.1007/s00125-016-3989-1
language
English
LU publication?
yes
id
c65b8508-8eb3-4d35-bc0e-74d868491350
date added to LUP
2016-06-17 16:48:53
date last changed
2017-09-10 05:07:03
@article{c65b8508-8eb3-4d35-bc0e-74d868491350,
  abstract     = {<p>Aims/hypothesis: The aim of this study was to assess the interaction between melatonin receptor 1B gene (MTNR1B) rs10830963 polymorphism and lifestyle intervention during pregnancy on occurrence of gestational diabetes mellitus (GDM) in high-risk women. Methods: This is a secondary analysis of the randomised controlled gestational diabetes prevention trial ‘RADIEL’, conducted between 2008 and 2014 in four maternity hospitals in southern Finland. A total of 226 women with a history of GDM and/or a pre-pregnancy BMI ≥ 30 kg/m<sup>2</sup> were enrolled at </p>},
  author       = {Grotenfelt, Nora E. and Wasenius, Niko S. and Rönö, Kristiina and Laivuori, Hannele and Stach-Lempinen, Beata and Orho-Melander, Marju and Schulz, Christina Alexandra and Kautiainen, Hannu and Koivusalo, Saila B. and Eriksson, Johan G.},
  issn         = {0012-186X},
  keyword      = {Clinical trial,Diabetes,Gestational,Melatonin,MT2,Polymorphism,Pregnancy,Prevalence,Public health,Receptor,Single nucleotide},
  language     = {eng},
  number       = {8},
  pages        = {1655--1658},
  publisher    = {Springer Verlag},
  series       = {Diabetologia},
  title        = {Interaction between rs10830963 polymorphism in MTNR1B and lifestyle intervention on occurrence of gestational diabetes},
  url          = {http://dx.doi.org/10.1007/s00125-016-3989-1},
  volume       = {59},
  year         = {2016},
}