One-view digital breast tomosynthesis as a stand-alone modality for breast cancer detection : do we need more?
(2018) In European Radiology 28(5). p.1938-1948- Abstract
Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. Materials and methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1–10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were... (More)
Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. Materials and methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1–10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were computed. Results: On average, 1v-DBT was non-inferior to any of the other protocols in terms of JAFROC figure-of-merit, area under ROC curve, sensitivity or specificity (p>0.391). While readers inexperienced with 1v-DBT screening improved their sensitivity when adding more images (69–79 %, p=0.019), experienced readers showed similar sensitivity (76 %) and specificity (70 %) between 1v-DBT and 2v-DM+2v-DBT (p=0.482). Subanalysis by lesion type and breast density showed no difference among modalities. Conclusion: Detection performance with 1v-DBT is not statistically inferior to 2v-DM or to 2v-DM+2v-DBT; its use as a stand-alone modality might be sufficient for readers experienced with this protocol. Key points: • One-view breast tomosynthesis is not inferior to two-view digital mammography.• One-view DBT is not inferior to 2-view DM plus 2-view DBT.• Training may lead to 1v-DBT being sufficient for screening.
(Less)
- author
- organization
- publishing date
- 2018-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Breast cancer, Digital breast tomosynthesis, Digital mammography, Jack-knife alternative free-response receiver operating characteristic, Receiver operating characteristic
- in
- European Radiology
- volume
- 28
- issue
- 5
- pages
- 1938 - 1948
- publisher
- Springer
- external identifiers
-
- scopus:85037710554
- pmid:29230524
- ISSN
- 0938-7994
- DOI
- 10.1007/s00330-017-5167-3
- language
- English
- LU publication?
- yes
- id
- c66fa912-c302-4271-82f6-34ddd3e25150
- date added to LUP
- 2018-01-04 12:33:24
- date last changed
- 2024-08-19 10:02:40
@article{c66fa912-c302-4271-82f6-34ddd3e25150, abstract = {{<p>Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. Materials and methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1–10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were computed. Results: On average, 1v-DBT was non-inferior to any of the other protocols in terms of JAFROC figure-of-merit, area under ROC curve, sensitivity or specificity (p>0.391). While readers inexperienced with 1v-DBT screening improved their sensitivity when adding more images (69–79 %, p=0.019), experienced readers showed similar sensitivity (76 %) and specificity (70 %) between 1v-DBT and 2v-DM+2v-DBT (p=0.482). Subanalysis by lesion type and breast density showed no difference among modalities. Conclusion: Detection performance with 1v-DBT is not statistically inferior to 2v-DM or to 2v-DM+2v-DBT; its use as a stand-alone modality might be sufficient for readers experienced with this protocol. Key points: • One-view breast tomosynthesis is not inferior to two-view digital mammography.• One-view DBT is not inferior to 2-view DM plus 2-view DBT.• Training may lead to 1v-DBT being sufficient for screening.</p>}}, author = {{Rodriguez-Ruiz, Alejandro and Gubern-Merida, Albert and Imhof-Tas, Mechli and Lardenoije, Susanne and Wanders, Alexander J.T. and Andersson, Ingvar and Zackrisson, Sophia and Lång, Kristina and Dustler, Magnus and Karssemeijer, Nico and Mann, Ritse M. and Sechopoulos, Ioannis}}, issn = {{0938-7994}}, keywords = {{Breast cancer; Digital breast tomosynthesis; Digital mammography; Jack-knife alternative free-response receiver operating characteristic; Receiver operating characteristic}}, language = {{eng}}, number = {{5}}, pages = {{1938--1948}}, publisher = {{Springer}}, series = {{European Radiology}}, title = {{One-view digital breast tomosynthesis as a stand-alone modality for breast cancer detection : do we need more?}}, url = {{http://dx.doi.org/10.1007/s00330-017-5167-3}}, doi = {{10.1007/s00330-017-5167-3}}, volume = {{28}}, year = {{2018}}, }