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Effectiveness of Behaviour Therapy for Children and Adolescents with Tourette Syndrome and Chronic Tic Disorder in a Naturalistic Setting

Andrén, Per LU ; Wachtmeister, Vera ; Franzé, Julia ; Speiner, Caroline ; Fernández de la Cruz, Lorena ; Andersson, Erik ; de Schipper, Elles ; Rautio, Daniel ; Silverberg-Mörse, Maria and Serlachius, Eva LU , et al. (2021) In Child Psychiatry and Human Development 52(4). p.739-750
Abstract

It is unclear if the results of randomised controlled trials (RCTs) of behaviour therapy (BT) for Tourette syndrome (TS) and chronic tic disorder (CTD) can be generalised to naturalistic clinical settings and are durable long-term. In this naturalistic study, 74 young people with TS/CTD received BT at a specialist clinic. Data were collected at baseline, post-treatment, and at 3-, 6-, and 12-month follow-ups. Measures included the Yale Global Tic Severity Scale (YGTSS) and the Clinical Global Impression-Improvement scale (CGI-I), amongst others. Tic severity and tic-related impairment improved after treatment, with large within-group effect sizes. At post-treatment, 57% of the participants were classified as treatment responders... (More)

It is unclear if the results of randomised controlled trials (RCTs) of behaviour therapy (BT) for Tourette syndrome (TS) and chronic tic disorder (CTD) can be generalised to naturalistic clinical settings and are durable long-term. In this naturalistic study, 74 young people with TS/CTD received BT at a specialist clinic. Data were collected at baseline, post-treatment, and at 3-, 6-, and 12-month follow-ups. Measures included the Yale Global Tic Severity Scale (YGTSS) and the Clinical Global Impression-Improvement scale (CGI-I), amongst others. Tic severity and tic-related impairment improved after treatment, with large within-group effect sizes. At post-treatment, 57% of the participants were classified as treatment responders according to the CGI-I. Tic severity and tic-related impairment improved further through the follow-up, with 75% treatment responders at the 12-month follow-up. BT is an effective and durable treatment for young people with TS/CTD in a naturalistic specialist clinical setting, with comparable effects to RCTs.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Behaviour therapy, Exposure with response prevention, Habit reversal training, Tic disorders, Tourette syndrome
in
Child Psychiatry and Human Development
volume
52
issue
4
pages
739 - 750
publisher
Springer
external identifiers
  • pmid:33315190
  • scopus:85106765256
ISSN
0009-398X
DOI
10.1007/s10578-020-01098-y
language
English
LU publication?
no
additional info
Publisher Copyright: © 2020, The Author(s).
id
c6fdae4f-9f64-4e48-801d-244652070f6a
date added to LUP
2023-07-14 11:37:26
date last changed
2024-04-05 21:06:24
@article{c6fdae4f-9f64-4e48-801d-244652070f6a,
  abstract     = {{<p>It is unclear if the results of randomised controlled trials (RCTs) of behaviour therapy (BT) for Tourette syndrome (TS) and chronic tic disorder (CTD) can be generalised to naturalistic clinical settings and are durable long-term. In this naturalistic study, 74 young people with TS/CTD received BT at a specialist clinic. Data were collected at baseline, post-treatment, and at 3-, 6-, and 12-month follow-ups. Measures included the Yale Global Tic Severity Scale (YGTSS) and the Clinical Global Impression-Improvement scale (CGI-I), amongst others. Tic severity and tic-related impairment improved after treatment, with large within-group effect sizes. At post-treatment, 57% of the participants were classified as treatment responders according to the CGI-I. Tic severity and tic-related impairment improved further through the follow-up, with 75% treatment responders at the 12-month follow-up. BT is an effective and durable treatment for young people with TS/CTD in a naturalistic specialist clinical setting, with comparable effects to RCTs.</p>}},
  author       = {{Andrén, Per and Wachtmeister, Vera and Franzé, Julia and Speiner, Caroline and Fernández de la Cruz, Lorena and Andersson, Erik and de Schipper, Elles and Rautio, Daniel and Silverberg-Mörse, Maria and Serlachius, Eva and Mataix-Cols, David}},
  issn         = {{0009-398X}},
  keywords     = {{Behaviour therapy; Exposure with response prevention; Habit reversal training; Tic disorders; Tourette syndrome}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{739--750}},
  publisher    = {{Springer}},
  series       = {{Child Psychiatry and Human Development}},
  title        = {{Effectiveness of Behaviour Therapy for Children and Adolescents with Tourette Syndrome and Chronic Tic Disorder in a Naturalistic Setting}},
  url          = {{http://dx.doi.org/10.1007/s10578-020-01098-y}},
  doi          = {{10.1007/s10578-020-01098-y}},
  volume       = {{52}},
  year         = {{2021}},
}