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Rules and Tools in the Battle against Superbugs - A call for integrated strategies and enhanced international collaboration to promote antimicrobial drug development

Minssen, Timo and Nordberg, Ana LU orcid (2020) p.111-136
Abstract
The lack of treatments during the recent Ebola and Zika outbreaks dramatically exposed the vulnerability of the global health system and the dire consequences thereof. But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). A growing number of microbial organisms are becoming resistant to available drugs with increasingly diverse risks for a rapid global spreading of infections. Unfortunately, the traditional IP based innovation system and regulatory frameworks do not provide sufficient incentives to invest in the development of new antimicrobials. Hence, there are few new treatments in the pipeline to replace a growing number of... (More)
The lack of treatments during the recent Ebola and Zika outbreaks dramatically exposed the vulnerability of the global health system and the dire consequences thereof. But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). A growing number of microbial organisms are becoming resistant to available drugs with increasingly diverse risks for a rapid global spreading of infections. Unfortunately, the traditional IP based innovation system and regulatory frameworks do not provide sufficient incentives to invest in the development of new antimicrobials. Hence, there are few new treatments in the pipeline to replace a growing number of ineffective drugs or problematic drug combinations. Repairing these broken economic incentives, improving access to and sustaining the effectiveness of antimicrobials is among the most important challenges in the health and life sciences. In this paper we emphasize that this goal can only be achieved through integrated strategies and a better global coordination of interdisciplinary multi-sector responses. (Less)
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author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Private law, Regulatory pathways, Accelerators, IPRs, Antimicrobials, Resistance, Sustainable incentives, Civilrätt
host publication
Infectious Diseases in the New Millennium: Legal and Ethical Challenges
editor
Eccleston-Turner, Mark and Brassington, Iain
pages
26 pages
publisher
Springer
ISBN
978-3-030-39818-7
978-3-030-39819-4
DOI
10.1007/978-3-030-39819-4_6
language
English
LU publication?
yes
id
c7017cb8-fb15-45d0-812a-82a4fe78de47
date added to LUP
2018-01-11 09:59:18
date last changed
2022-10-10 10:31:34
@inbook{c7017cb8-fb15-45d0-812a-82a4fe78de47,
  abstract     = {{The lack of treatments during the recent Ebola and Zika outbreaks dramatically exposed the vulnerability of the global health system and the dire consequences thereof. But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). A growing number of microbial organisms are becoming resistant to available drugs with increasingly diverse risks for a rapid global spreading of infections. Unfortunately, the traditional IP based innovation system and regulatory frameworks do not provide sufficient incentives to invest in the development of new antimicrobials. Hence, there are few new treatments in the pipeline to replace a growing number of ineffective drugs or problematic drug combinations. Repairing these broken economic incentives, improving access to and sustaining the effectiveness of antimicrobials is among the most important challenges in the health and life sciences.  In this paper we emphasize that this goal can only be achieved through integrated strategies and a better global coordination of interdisciplinary multi-sector responses.}},
  author       = {{Minssen, Timo and Nordberg, Ana}},
  booktitle    = {{Infectious Diseases in the New Millennium: Legal and Ethical Challenges}},
  editor       = {{Eccleston-Turner, Mark and Brassington, Iain}},
  isbn         = {{978-3-030-39818-7}},
  keywords     = {{Private law; Regulatory pathways; Accelerators; IPRs; Antimicrobials; Resistance; Sustainable incentives; Civilrätt}},
  language     = {{eng}},
  month        = {{05}},
  pages        = {{111--136}},
  publisher    = {{Springer}},
  title        = {{Rules and Tools in the Battle against Superbugs - A call for integrated strategies and enhanced international collaboration to promote antimicrobial drug development}},
  url          = {{http://dx.doi.org/10.1007/978-3-030-39819-4_6}},
  doi          = {{10.1007/978-3-030-39819-4_6}},
  year         = {{2020}},
}