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Dose integration and dose rate characteristics of a NiPAM polymer gel MRI dosimeter system

Waldenberg, C.; Karlsson Hauer, A.; Gustafsson, Christian LU and Ceberg, S. LU (2017) In Journal of Physics: Conference Series 847(1).
Abstract

The normoxic polymer gel dosimeter based on N-isopropyl acrylamide (NiPAM) is a promising full 3D-dosimeter with high spatial resolution and near tissue equivalency. NiPAM gel samples were irradiated to different doses using a linear accelerator. The absorbed dose was evaluated using MRI and statistical significance of the analysed data was calculated. The analysis was carried out using an in-house developed software. It was found that the gel dosimeter responded linearly to the absorbed dose. The gel exhibited a dose rate dependence, as well as a dependence on the sequential beam irradiation scheme. A higher dose rate, as well as a higher dose per sequential beam, resulted in a lower dose response.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Physics: Conference Series
volume
847
issue
1
publisher
IOP Publishing
external identifiers
  • scopus:85022100791
ISSN
1742-6588
DOI
10.1088/1742-6596/847/1/012063
language
English
LU publication?
yes
id
c72cb002-5ece-4475-93cf-da8bb99f4fca
date added to LUP
2017-07-24 12:25:28
date last changed
2017-07-24 12:25:28
@article{c72cb002-5ece-4475-93cf-da8bb99f4fca,
  abstract     = {<p>The normoxic polymer gel dosimeter based on N-isopropyl acrylamide (NiPAM) is a promising full 3D-dosimeter with high spatial resolution and near tissue equivalency. NiPAM gel samples were irradiated to different doses using a linear accelerator. The absorbed dose was evaluated using MRI and statistical significance of the analysed data was calculated. The analysis was carried out using an in-house developed software. It was found that the gel dosimeter responded linearly to the absorbed dose. The gel exhibited a dose rate dependence, as well as a dependence on the sequential beam irradiation scheme. A higher dose rate, as well as a higher dose per sequential beam, resulted in a lower dose response.</p>},
  articleno    = {012063},
  author       = {Waldenberg, C. and Karlsson Hauer, A. and Gustafsson, Christian and Ceberg, S.},
  issn         = {1742-6588},
  language     = {eng},
  month        = {06},
  number       = {1},
  publisher    = {IOP Publishing},
  series       = {Journal of Physics: Conference Series},
  title        = {Dose integration and dose rate characteristics of a NiPAM polymer gel MRI dosimeter system},
  url          = {http://dx.doi.org/10.1088/1742-6596/847/1/012063},
  volume       = {847},
  year         = {2017},
}