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An automated image-collection system for crystallization experiments using SBS standard microplates

Brostromer, Erik; Nan, Jie LU and Su, Xiao Dong LU (2007) In Acta Crystallographica. Section D: Biological Crystallography 63(Pt 2). p.25-119
Abstract

As part of a structural genomics platform in a university laboratory, a low-cost in-house-developed automated imaging system for SBS microplate experiments has been designed and constructed. The imaging system can scan a microplate in 2-6 min for a 96-well plate depending on the plate layout and scanning options. A web-based crystallization database system has been developed, enabling users to follow their crystallization experiments from a web browser. As the system has been designed and built by students and crystallographers using commercially available parts, this report is aimed to serve as a do-it-yourself example for laboratory robotics.

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author
organization
publishing date
type
Contribution to journal
publication status
published
keywords
Automation, Crystallization, Data Collection, Databases, Factual, Diagnostic Imaging, Genomics, Microarray Analysis, Robotics
in
Acta Crystallographica. Section D: Biological Crystallography
volume
63
issue
Pt 2
pages
7 pages
publisher
International Union of Crystallography
external identifiers
  • scopus:33846685212
ISSN
0907-4449
DOI
10.1107/S0907444906042442
language
English
LU publication?
yes
id
c8d80748-4f4b-4b62-8c54-07e455603443
date added to LUP
2016-09-07 22:54:31
date last changed
2017-01-01 08:33:34
@article{c8d80748-4f4b-4b62-8c54-07e455603443,
  abstract     = {<p>As part of a structural genomics platform in a university laboratory, a low-cost in-house-developed automated imaging system for SBS microplate experiments has been designed and constructed. The imaging system can scan a microplate in 2-6 min for a 96-well plate depending on the plate layout and scanning options. A web-based crystallization database system has been developed, enabling users to follow their crystallization experiments from a web browser. As the system has been designed and built by students and crystallographers using commercially available parts, this report is aimed to serve as a do-it-yourself example for laboratory robotics.</p>},
  author       = {Brostromer, Erik and Nan, Jie and Su, Xiao Dong},
  issn         = {0907-4449},
  keyword      = {Automation,Crystallization,Data Collection,Databases, Factual,Diagnostic Imaging,Genomics,Microarray Analysis,Robotics},
  language     = {eng},
  number       = {Pt 2},
  pages        = {25--119},
  publisher    = {International Union of Crystallography},
  series       = {Acta Crystallographica. Section D: Biological Crystallography},
  title        = {An automated image-collection system for crystallization experiments using SBS standard microplates},
  url          = {http://dx.doi.org/10.1107/S0907444906042442},
  volume       = {63},
  year         = {2007},
}