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Gender differences in subtypes of depression by first incidence and age of onset : a follow-up of the Lundby population

Bogren, Mats LU ; Brådvik, Louise LU ; Holmstrand, Cecilia LU ; Nöbbelin, Linnéa LU and Mattisson, Cecilia LU (2018) In Archiv fur Psychiatrie und Nervenkrankheiten 268(2). p.179-189
Abstract

The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher than males for most subtypes of depression. However, for depression with melancholic and/or psychotic features, the overall first incidence rate did not differ significantly between the genders. The mean age of onset did not differ significantly between females and males in any of the depressive subtypes. Nevertheless, females and males had... (More)

The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher than males for most subtypes of depression. However, for depression with melancholic and/or psychotic features, the overall first incidence rate did not differ significantly between the genders. The mean age of onset did not differ significantly between females and males in any of the depressive subtypes. Nevertheless, females and males had different first incidence rates by age of onset patterns for unipolar non-melancholic DSM-IV mood disorder and major depressive disorder (MDD), with a consistent gender incidence gap across all ages, but with the most conspicuous gender gap in middle age. The first incidence rates by age of onset patterns for DSM-IV MDD with melancholic and/or psychotic features did not differ significantly between the genders. The findings support that females are more prone than males to develop depression with medium severity, but no gender differences were found in melancholic and/or psychotic depression. The findings may support that unipolar non-melancholic depression and melancholic and/or psychotic depression represents different disorders. Tentative explanations for this are discussed.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Journal Article
in
Archiv fur Psychiatrie und Nervenkrankheiten
volume
268
issue
2
pages
179 - 189
publisher
Springer
external identifiers
  • scopus:85015667632
ISSN
0003-9373
DOI
10.1007/s00406-017-0778-x
language
English
LU publication?
yes
id
c94d91f6-d55b-4565-8d54-c9318eede29d
date added to LUP
2017-08-04 19:32:35
date last changed
2018-05-05 03:00:18
@article{c94d91f6-d55b-4565-8d54-c9318eede29d,
  abstract     = {<p>The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher than males for most subtypes of depression. However, for depression with melancholic and/or psychotic features, the overall first incidence rate did not differ significantly between the genders. The mean age of onset did not differ significantly between females and males in any of the depressive subtypes. Nevertheless, females and males had different first incidence rates by age of onset patterns for unipolar non-melancholic DSM-IV mood disorder and major depressive disorder (MDD), with a consistent gender incidence gap across all ages, but with the most conspicuous gender gap in middle age. The first incidence rates by age of onset patterns for DSM-IV MDD with melancholic and/or psychotic features did not differ significantly between the genders. The findings support that females are more prone than males to develop depression with medium severity, but no gender differences were found in melancholic and/or psychotic depression. The findings may support that unipolar non-melancholic depression and melancholic and/or psychotic depression represents different disorders. Tentative explanations for this are discussed.</p>},
  author       = {Bogren, Mats and Brådvik, Louise and Holmstrand, Cecilia and Nöbbelin, Linnéa and Mattisson, Cecilia},
  issn         = {0003-9373},
  keyword      = {Journal Article},
  language     = {eng},
  number       = {2},
  pages        = {179--189},
  publisher    = {Springer},
  series       = {Archiv fur Psychiatrie und Nervenkrankheiten},
  title        = {Gender differences in subtypes of depression by first incidence and age of onset : a follow-up of the Lundby population},
  url          = {http://dx.doi.org/10.1007/s00406-017-0778-x},
  volume       = {268},
  year         = {2018},
}